cell carcinomas, those with a prominent tumor-associated lymphoid proliferation may actually be more indolent.
cell carcinoma was diagnosed in 4 (3.50%) cases, 2 cases each were seen in parotid and submandibular glands and was seen in 3rd and 5th decade which is similar to the study conducted by Fernandes GC et al.15 Two case of adenoid cystic carcinoma were diagnosed involving the minor salivary glands which are also similar to other studies .
(1.) Al-Zaher N et al: Acinic
cell carcinoma of the salivary glands: a literature review.
cell carcinoma of the mandible: Report of a case.
Westra, "Most nonparotid 'acinic
cell carcinomas' represent mammary analog secretory carcinomas," The American Journal of Surgical Pathology, vol.
The commonest malignant tumor was mucoepidermoid carcinoma 5 (6.41%), followed by adenoid cystic carcinoma 3 (3.84%), acinic
cell carcinoma 2 (2.56%), malignant mixed tumor and large duct adenocarcinoma one (1.28%) case each.
Among these patients, seven (53.8%) cases were adenoid cystic carcinoma, three (23.1%) were mucoepidermoid carcinoma and three (23.1%) were acinic
Adenocarcinomas and acinic
cell carcinomas often show deletions of 6q and trisomies for chromosomes 7 or 8, in mucoepidermoid carcinomas a recurrent t(11;19)(q14-21;p12) has been described, adenoid cystic carcinomas are characterized by a recurrent t(6;9) (q21-24;p22-24) or del(6q), and carcinomas arising from pleomorphic adenomas usually have structural rearrangements resembling those in pleomorphic adenomas together with other structural or numerical abnormalities, such as polyploidization, indicating that the malignant transformation often is paralleled by cytogenetically visible clonal evolution.
We assume that an increase in NO concentration in the saliva of patients with RA can occur due to inflammatory processes acinic
and ductal epithelial cells of salivary glands and, consequently, increased iNOS activity of inflamed tissue, under whose influence the NO produced in higher concentrations.
We have demonstrated that the distribution of mucous alveoli is greater than serous acini, which are mainly located at the basal membrane of acinic
Minor discordance encompassed the following situations: (1) FNA diagnosis of benign/low-grade neoplasm with corresponding surgical pathology/flow cytometry demonstrating a different but also benign/low-grade neoplasm (eg, FNA diagnosis of cellular pleomorphic adenoma and corresponding surgical pathology showing basal cell adenoma); (2) FNA diagnosis of malignant neoplasm with corresponding surgical pathology/flow cytometry/cytogenetics showing a different malignant neoplasm (eg, FNA diagnosis of "salivary gland carcinoma, favor acinic
cell carcinoma," and corresponding surgical pathology showing salivary duct carcinoma); and (3) nondiagnostic FNA with corresponding surgical pathology showing benign lesion with inherent low cellularity (eg, pseudocyst).
Epithelial component shows varied patterns like Cylindromatous pattern as seen in Basal cell carcinoma, Adenoid cystic carcinoma and Acinic