diaphyseal aclasis

(redirected from aclasis)
Also found in: Medical.

diaphyseal aclasis

[dī′af·sē·əl ′ak·lə·səs]
References in periodicals archive ?
Multiple hereditary exostoses (MHE) also referred to as diaphyseal aclasis or familial osteochondromatosis is a rare autosomal dominant skeletal disorder with almost complete penetrance (95%) due to loss of functional mutations in two genes: exostosin-1 (EXT-1) and exostosin-2 (EXT-2) genotypes [1].
Diaphyseal aclasis, also termed Hereditary Multiple Exostosis (HME) or osteochondromatosis is characterised by multiple bony prominences that grow near joint lines throughout the skeleton.
Malignant change in a previously benign tumour is largely restricted to conditions such as multiple exostoses (diaphyseal aclasis) and multiple enchondromatosis or Ollier's disease, where a relatively slow-growing chondrosarcoma develops in middle age.
The disease congenital diaphyseal aclasis was considered but the growths usually join the bone at right angles to the bone shaft (Edeiken & Hodes 1967: 104, 107).
Nhereditary Multiple Exostoses (HME, EXT, MHE, Diaphyseal Aclasis, Familial Bony Spurs) is usually, but not necessarily, an inherited condition which can produce bony lumps close to the end of any bone, but particularly those of the limbs
l The support group can be contacted on 01438 861866 or by email at hmesg@ox 1.co.uk FACT FILE What is Hereditary Multiple Exostoses?Hereditary Multiple Exostoses (also known as HME, EXT, MHE, Diaphyseal Aclasis, Familial Bony Spurs) is a condition which can produce bony lumps close to the end of any bone, but particularly those of the limbs.