keratosis

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keratosis

[‚ker·ə′tō·səs]
(medicine)
Any disease of the skin characterized by an overgrowth of the cornified epithelium.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Ferguson, "Actinic Keratosis Clinical Practice Guidelines: An Appraisal of Quality," Dermatology Research and Practice, vol.
Actinic keratosis (AK) is defined as the neoplastic transformation and proliferation of keratinocytes within the epidermis without breaching the basement membrane [1].
Caption: Side effects of actinic keratosis therapy can affect patient adherence.
Cryotherapy has been a most common destructive method in treatment of actinic keratosis lesions2,7 and is simple and low cost.8-10 Improvement rate of lesions with cryotherapy has been reported between 75-98 percent.11 In some studies, topical retinoid has been effective in improvement of clinical demonstrations of sunlight-damaged skins including actinic keratosis.12,13
However, participants who consumed the highest amounts of oily fish showed a 28% decrease in acquisition of actinic keratosis compared with minimal fish intake.
She had developed Actinic Keratosis which normally only affects people in their 70s or 80s who have worked outdoors for hours in baking sun.
Such diseases may include, but are not limited to, psoriasis, rheumatoid arthritis, emphysema, asthma, diabetes, autoimmune thyroiditis, inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, different types of dermatitis including allergic dermatitis, contact dermatitis, actinic keratosis, wound healing, scar formation, various renal diseases, various respiratory diseases, various diseases of reproductive organs, such as endometriosis, melanoma, squamous cell carcinoma, ovarian cancer, breast cancer, lung cancer, colon cancer, prostate cancer, renal cell carcinoma, Grave's diseases and other inflammatory and hyperproliferative diseases.
Its lead drug candidate, a topical gel known as PEP005, is intended to serve as a less-costly alternative to surgical treatments for a common pre-cancerous skin condition known as actinic keratosis (AK).
Chemical peels, in which chemical solutions are placed on the face, causing the outer layers of damaged skin to blister and peel off, also can reduce wrinkles and get rid of some pre-cancerous spots, known as actinic keratosis, which appear as little, red, scaly bumps.
In the study by Carag et al (6) step sections (10 slides at 50-[micro]m intervals) revealed new diagnostic findings in 33% of biopsies with an initial diagnosis of actinic keratosis. In our study, step sections (3 slides at 50-[micro]m intervals) resulted in new findings in 7% of small skin biopsies or curettings.
Actinic keratosis is likely underdiagnosed and underreported, partially because separating AK from SCC is a challenge and partially because it is difficult to track, since reports of AK diagnosis are not included in cancer registries.