Nonetheless, the positive control actinomycin
D (I[C.sub.50] =0.0022 [micro]g/ml) showed higher activity compared to N2.
(a) Real-time of TrxR1 mRNA in HUVECs treated with [H.sub.2][O.sb.2] and/or actinomycin
A comparable observation was reported by Ivana et al (10) who analysed the fragementation patterns of actinomycin
D, demethylact D and Didemethlyact D through PSD-MALDI-TOF mass spectrometry.
A general transcription inhibitor actinomycin
D normalized the downregulation of TP receptor-mediated contractions, suggesting involvement of transcriptional mechanisms.
Bergeron et al., "The IVADo regimen--a pilot study with ifosfamide, vincristine, actinomycin
D, and doxorubicin in children with metastatic soft tissue sarcoma: a pilot study on behalf of the European Pediatric Soft Tissue Sarcoma Study Group," Cancer, vol.
The degradation rate of YFP mRNA was detected with actinomycin
D treatment via qRT-PCR.
To evaluate if the enhanced level of MKP-1 protein in the presence of curcumin is a consequence of increased MKP-1 transcription, we employed Actinomycin
D (ACT-D), a transcription inhibitor.
Vincristine and actinomycin
D are the most frequently employed agents.
He was treated with right radical orchiectomy and adjuvant chemotherapy (three cycles of bleomycin, actinomycin
, cisplatin, and vinblastine).
, and cyclophosphamide compared with vincristine, actinomycin
, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: Children's Oncology Group study D9803.
Thus, the present study aimed to evaluate the MDR-modulatory activity of the quercetin-POM conjugates 2 and 3 on the antitumor activity of the anticancer agents doxorubicin, actinomycin
D, vinblastine, and paditaxel against MDR cancer cell lines.
It is known that drugs: actinomycin
D, doxorubicin, the cis-platin, hydroxyurea and nitrosoureas cause diarrhea .