activating enzyme


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activating enzyme

[′ak·tə‚vād·iŋ ′en‚zīm]
(biochemistry)
An enzyme that catalyzes a reaction involving adenosine triphosphate and a specific amino acid to give a product that subsequently reacts with a specific transfer ribonucleic acid.
References in periodicals archive ?
Pharmacodynamic and efficacy relationship of MLN4924, a novel small molecule inhibitor of Nedd8-activating enzyme, in human xenograft tumors grown in immunocompromised mice -- Lead investigator: Allison Berger, Senior Scientist, Millennium -- Abstract #85: Poster -- MLN4924, a potent and novel small molecule inhibitor of Nedd8 activating enzyme, induces DNA re-replication and apoptosis in cultured human tumor cells -- Lead investigator: Michael Millhollen, Scientist, Millennium -- Abstract #356: Poster MLN8237
When it binds to calcium, it starts activating enzymes and thus serves as an intermediate messenger that amplifies chemical cascades inside a cell.
Our research also found that compounds similar to MLN4924 form analogous adducts that inhibit activating enzymes related to NAE.
Activating Enzymes for Use in Organic Solvents (Anne L.

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