acute rejection, acute tubular necrosis
and nephrotoxicity, B-mode ultrasound presentation can be identical (5).
1 Time since being envenomed (h) Geographic Locations NRP CRP SARP WRP SAP Congestion of glomeruli + + 0 0 0 Acute tubular necrosis
+ + 0 0 0 Capillary congestion + + + + + Infiltration of inflammatory cells + + 0 + + 3 Time since being envenomed (h) Geographic Locations NRP CRP SARP WRP SAP Congestion of glomeruli ++ ++ + + + Acute tubular necrosis
++ ++ + + + Capillary congestion ++ ++ + + + Infiltration of inflammatory cells ++ + + ++ + 6 Time since being envenomed (h) Geographic Locations NRP CRP SARP WRP SAP Congestion of glomeruli +++ ++ ++ + + Acute tubular necrosis
+++ ++ + + + Capillary congestion ++ ++ + + + Infiltration of inflammatory cells ++ ++ + + + Table 5: Major histopathological changes in liver by N.
Acute tubular necrosis
is a syndrome of physiologic and pathologic dissociation.
Acute tubular necrosis
is the most common renal AKI seen in lymphoma patients, with lysozyme-induced tubular necrosis and tumour lysis syndrome being common etiologies (Luciano & Brewster, 2014).
Of note, his hospital course was further complicated by a left subclavian vein thrombosis, and acute tubular necrosis
, later requiring intermittent hemodialysis.
In our case, the diagnosis was delayed and our patient experienced myonecrosis with resulting myoglobinuria that required intensive care monitoring and resuscitation but did not progress to acute tubular necrosis
. While the patient discussed in this case returned for a six-month follow-up with no resultant long-term deficits in muscle function, the potential for irreversible tissue damage increases with increased duration and severity of the elevated compartment pressures.
Surgery was complicated by intraoperative hypotension resulting in acute tubular necrosis
and stage 3 acute kidney injury requiring continuous renal replacement therapy following transplantation.
These overall findings were consistent with mesangial proliferative lupus nephritis (Renal Pathology Society class II) and concomitant acute tubular necrosis
This showed acute tubular necrosis
and significant deposition of hemosiderin, as shown by positive Perls staining.
Previous AAN studies have mostly focused on the aristolochic acids- (AA-) induced acute tubular necrosis
and acute nephrotoxicity .
In acute tubular necrosis
(ATN) tubular lumen is obstructed by casts formed by aggregation of polymers of "Tamm-Horsfall protein" and cellular debris; this protein is normally secreted by tubular cells as monomer but in ATN it become evident in histological sections.31
 Case 3 had a high creatine kinase level, presumably caused by seizure-induced rhabdomyolysis, which may have contributed to acute tubular necrosis