acute-phase reaction


Also found in: Medical.

acute-phase reaction

[ə¦kyüt ¦fāz rē′ak·shən]
(immunology)
During inflammation, change in the rates of synthesis of certain serum proteins that are important in nonspecific defense reactions.
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References in periodicals archive ?
Indications of an acute-phase reaction at the initial stages of infection were not detected.
Plasma protein, hematologic and blood chemistry changes in African grey parrots (Psittacus erithacus) experimentally infected with bornavirus
The hyperferritinemia in AOSD may not simply be secondary to the disease process as part of an acute-phase reaction, but could be causative in the condition, maybe involving iron-mediated oxidative damage or even a mutated form of ferritin.
Commentary
Some proteins (alpha 1 -antitrypsin, alpha 1-acid glycoprotein, haptoglobin, ceruloplasmin, C4, C3 and C-reactive protein) will increase in response to an acute-phase reaction and are known as positive acute- phase proteins.
Plasma proteins as biomarkers: acute phase proteins
Lipton, patients treated with denosumab had an 8% incidence of a flu-like, acute-phase reaction during the first 3 days after the start of treatment, compared with a 33% rate in patients randomized to treatment with an intravenous bisphosphonate.
Denosumab may be safer than IV bisphosphonates

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