acute-phase reaction


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acute-phase reaction

[ə¦kyüt ¦fāz rē′ak·shən]
(immunology)
During inflammation, change in the rates of synthesis of certain serum proteins that are important in nonspecific defense reactions.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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HDL and LDL cholesterol are depressed during sepsis as part of a cytokine-mediated acute-phase reaction (2).
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Indications of an acute-phase reaction at the initial stages of infection were not detected.
Plasma protein, haematologic and blood chemistry changes in African grey parrots (Psittacus erithacus) experimentally infected with bornavirus
Some proteins (alpha 1 -antitrypsin, alpha 1-acid glycoprotein, haptoglobin, ceruloplasmin, C4, C3 and C-reactive protein) will increase in response to an acute-phase reaction and are known as positive acute- phase proteins.
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Another acute-phase reaction, elevated levels of C-reactive protein, may occur.
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Under stable conditions, CRP concentrations reflect inflammation in the vasculature but are boosted in the acute phase of NSTEACS due to the acute-phase reaction resulting from myocardial necrosis.
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The hyperferritinemia in AOSD may not simply be secondary to the disease process as part of an acute-phase reaction, but could be causative in the condition, maybe involving iron-mediated oxidative damage or even a mutated form of ferritin.
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