acute-phase reaction


Also found in: Medical.

acute-phase reaction

[ə¦kyüt ¦fāz rē′ak·shən]
(immunology)
During inflammation, change in the rates of synthesis of certain serum proteins that are important in nonspecific defense reactions.
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References in periodicals archive ?
HDL and LDL cholesterol are depressed during sepsis as part of a cytokine-mediated acute-phase reaction (2).
A 69-Year-Old Woman with Markedly Decreased Cholesterol
Indications of an acute-phase reaction at the initial stages of infection were not detected.
Plasma protein, haematologic and blood chemistry changes in African grey parrots (Psittacus erithacus) experimentally infected with bornavirus
Some proteins (alpha 1 -antitrypsin, alpha 1-acid glycoprotein, haptoglobin, ceruloplasmin, C4, C3 and C-reactive protein) will increase in response to an acute-phase reaction and are known as positive acute- phase proteins.
Plasma proteins as biomarkers: acute phase proteins
Another acute-phase reaction, elevated levels of C-reactive protein, may occur.
Derm diagnosis. (Clinical Rounds)
Under stable conditions, CRP concentrations reflect inflammation in the vasculature but are boosted in the acute phase of NSTEACS due to the acute-phase reaction resulting from myocardial necrosis.
Serial Measurement of Biomarkers after Acute Coronary Syndrome: Which One to Choose?
The hyperferritinemia in AOSD may not simply be secondary to the disease process as part of an acute-phase reaction, but could be causative in the condition, maybe involving iron-mediated oxidative damage or even a mutated form of ferritin.
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