Our sequencing of CHIKV genomes confirmed spread of an Asian lineage strain from the Caribbean and suggested that although CHIKV has circulated in the Americas since 2013, no adaptive mutations
These analyses will provide insight into the diversity of H5N1 quasispecies and the molecular mechanisms of human adaptive mutations
Drugs that interfere with it thus could limit "the potential for development of drug resistance that can occur due to rapid adaptive mutations
of viral genomes," the scientists state.
The H7N9 virus acquires selective adaptive mutations
while moving across people, the report added.
He notes that biology recognizes chance in such areas as adaptive mutations
, but not in the ebb and flow of social interaction.
Although apparently adaptive mutations
such as these arose in the past 10,000 years, some geneticists doubt that the agricultural revolution jump-started the pace of genetic evolution.
and replacements of virulence traits in the Escherichia coli O104:H4 outbreak population.
Yet the idea of adaptive mutations
flies in the face of a lot of orthodox genetics, which is why it's considered controversial.
Sequential adaptive mutations
enhance efficient vector switching by chikungunya virus and its epidemic emergence.
This contrasts the traditional Darwinistic view that they are the result of natural selection in favour of adaptive mutations
To elucidate the potential adaptive mutations
of the pandemic (H1N1) 2009 viruses, we studied the amino acid sequences of pandemic (H1N1) 2009 viruses at the positions that represent the so-called species-specific signatures of avian and human viruses.
We have previously described variations in putative anti-mutator genes in Beijing/W isolates that may have favored adaptive mutations
in this family of strains.