adaptive mutations

adaptive mutations

[ə¦dap·tiv myü′tā·shənz]
(genetics)
Mutations conferring an advantage in a selective environment which arise after nongrowing or slowly growing cells are exposed to the selective environment.
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References in periodicals archive ?
albopictus mosquitoes are concentrated in the subtropical southeastern states (10), which can lead to selection of different adaptive mutations in circulating CHIKV strains.
They cover anatomical and physiological aspects, clinical presentation, diagnosis and treatment, infections in children, the involvement of the vaginal microbiome, asymptomatic urinary tract infections, prostatitis, pyelonephritis, and urosepsis; reservoirs of infection, antimicrobial resistance, phylogeny, virulence, and fitness factors, including exotoxins, the structure of adhesins, adaptive mutations, and intracellular persistence, as well as other uropathogens; and host responses and emerging therapeutics, including innate immunity, sensation and pain in the bladder, and drug and vaccine development.
Take, for instance, the evolutionary synthesis's view of species as gene pools, in which evolution is a process of trial and error where the proportion of adaptive mutations increases over time: such a view is not possible without natural selection.
Wright, "Stress-Directed Adaptive Mutations and Evolution," Molecular Microbiology 52, no.
These analyses will provide insight into the diversity of H5N1 quasispecies and the molecular mechanisms of human adaptive mutations.
Drugs that interfere with it thus could limit "the potential for development of drug resistance that can occur due to rapid adaptive mutations of viral genomes," the scientists state.
The H7N9 virus acquires selective adaptive mutations while moving across people, the report added.
He notes that biology recognizes chance in such areas as adaptive mutations, but not in the ebb and flow of social interaction.
Although apparently adaptive mutations such as these arose in the past 10,000 years, some geneticists doubt that the agricultural revolution jump-started the pace of genetic evolution.
Although genetic analysis of experimental lines has provided a great deal of information about deleterious alleles, analogous analysis of adaptive mutations would typically require crosses between real taxa.

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