adaptor protein


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adaptor protein

[ə′dap·tər ‚prō‚tēn]
(cell and molecular biology)
A specialized protein that links protein components of the signaling pathway, thereby aiding intracellular signal transduction.
References in periodicals archive ?
Background: XB130 is a recently discovered adaptor protein that is highly expressed in many malignant tumors, but few studies have investigated its role in hepatocellular carcinoma (HCC).
Self-nucleic acids (RNA and DNA) or damaged nucleic acids can also trigger cGAS to produce 2'3'-cGAMP, which binds tightly to the adaptor protein STING (stimulator of interferon genes).
The last decade was characterized by a growing scientific interest for the members of the Crk-associated substrate (CAS) adaptor protein family, namely p130Cas/BCAR1 and NEDD9/HEF1/Cas-L.
When cytochrome c is released into the cytosol, it binds to an adaptor protein and pro-caspase-9, which in turn cleaves the procaspase-9 into the active form (25).
Li et al., "The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation," Immunity, vol.
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.
The modular adaptor protein ARH is required for low density lipoprotein (LDL) binding and internalization but not for LDL receptor clustering in coated pits.
Conclusion:MyD88-adaptor-like/TIR domain containing adaptor protein polymorphism for single nucleotide polymorphism rs8177374 is related with the susceptibility of malaria.
Different up-regulated proteins during the disease include insulin growth factor (IGF) II, a disintegrin and metalloproteases (ADAM) 9, signal transducers and activators of transcription (STAT) 3, suppressors of cytokine signalling (SOCS) 3, and cyclin D1 while the down-regulated proteins during the disease include collagen I, SMAD 4, fragile histidine triad (FHIT), and SOCS1.17 Other proteins include, POU class 5 homeobox 1 (OCT4), baculoviral IAP repeat containing 5 (BIRC5), cyclin D1 (CCND1), ATP binding cassette subfamily G member 2 (BCRP), SRY-box 2 (Sox2), Glutathione S-transferases (GST), NCK adaptor protein 1 (NCK1), human leukocyte antigen DQ (HLA-DQ), miR-106b, c-Myc, Ki67 and selective internal radiation therapy (SIRT).
OBSL1 encodes for a cytoskeletal adaptor protein which is localized within the prenuclear region.
Previous studies have shown that the clathrin adaptor protein complex 2 (AP-2) is essential for constitutive receptor internalization and cellular recovery of thrombin signaling [13].
Next, we assessed the effects of RNases, RNA, and RNA fragments on MyD88 adaptor protein expression.
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