adaptor protein


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adaptor protein

[ə′dap·tər ‚prō‚tēn]
(cell and molecular biology)
A specialized protein that links protein components of the signaling pathway, thereby aiding intracellular signal transduction.
References in periodicals archive ?
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.
sup][1] p66Shc is a 66-kDa Src collagen homolog (Shc) adaptor protein that is one of the three main isoforms encoded by the SHC1 gene (p46Shc, p52Shc, and p66Shc).
Conclusion:MyD88-adaptor-like/TIR domain containing adaptor protein polymorphism for single nucleotide polymorphism rs8177374 is related with the susceptibility of malaria.
The modular adaptor protein ARH is required for low density lipoprotein (LDL) binding and internalization but not for LDL receptor clustering in coated pits.
17 Other proteins include, POU class 5 homeobox 1 (OCT4), baculoviral IAP repeat containing 5 (BIRC5), cyclin D1 (CCND1), ATP binding cassette subfamily G member 2 (BCRP), SRY-box 2 (Sox2), Glutathione S-transferases (GST), NCK adaptor protein 1 (NCK1), human leukocyte antigen DQ (HLA-DQ), miR-106b, c-Myc, Ki67 and selective internal radiation therapy (SIRT).
Superoxide production is correlated with Gibbs free energy ([DELTA]G) p22-phox works as an adaptor protein between the membrane and the cytoplasmic components of the enzymatic complex (17), thus each truncated Nef protein was tested in order to determine whether the SH3 region or c-terminal were involved to mediate functional change in NOX2 NADPH-oxidase.
The research at the University of Louisville describes the role of TNF receptor-associated factor 6 (TRAF6), an adaptor protein and E3 ubiquitin ligase, in ensuring the vitality of stem cells that regenerate muscle tissue.
The structure of the Grb7 family of the adaptor protein is composite by a carboxylterminal src-homology 2 (SH2), GM domain and a proline-rich region.
SHC-1 is an adaptor protein that connects MLK-1 and its downstream MAPKK MEK-1.
Suppressor of cytokine signaling (SOCS) 5 utilises distinct domains for regulation of J AK1 and interaction with the adaptor protein Shc-1.
The adaptor protein Growth Receptor Bound protein-2 (Grb-2) is essential to cancer cell signaling because it is utilized by oncogenic tyrosine kinases to induce cancer progression.
Tumour protein D52 is a multi-functional adaptor protein that influences numerous cellular processes.
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