adenine


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adenine

(ăd`ənĭn, –nīn, –nēn), organic base of the purinepurine,
type of organic base found in the nucleotides and nucleic acids of plant and animal tissue. The German chemist Emil Fischer did much of the basic work on purines and introduced the term into the chemical literature in the early 20th cent.
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 family. Adenine combines with the sugar riboseribose
, monosaccharide carbohydrate of universal distribution in living tissue, found in ribonucleic acid (RNA; see nucleic acid), free nucleotides, and various coenzymes.
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 to form adenosine, which in turn can be bonded with from one to three phosphoric acid units, yielding the three nucleotides adenosine monophosphateadenosine monophosphate
(AMP) , organic compound composed of an adenine base, the sugar ribose, and one phosphate unit. AMP is one of the possible products of the hydrolysis of adenosine triphosphate (ATP) and is therefore important in the transfer of chemical energy during
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, adenosine diphosphate, and adenosine triphosphateadenosine triphosphate
(ATP) , organic compound composed of adenine, the sugar ribose, and three phosphate groups. ATP serves as the major energy source within the cell to drive a number of biological processes such as photosynthesis, muscle contraction, and the synthesis of
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. These adenine derivatives perform important functions in cellular metabolism. Adenine is one of four nitrogenous bases utilized in the synthesis of nucleic acidsnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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. A modified form of adenosine monophosphate is thought to be a secondary messenger in the propagation of many hormonal stimuli. Adenine is an integral part of the structure of many coenzymescoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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.

adenine

[′ad·ən‚ēn]
(biochemistry)
C5H5N5 A purine base, 6-aminopurine, occurring in ribonucleic acid and deoxyribonucleic acid and as a component of adenosine triphosphate.
References in periodicals archive ?
In general, conductivity values of all samples have no significant increment with and without adenine or thymine.
Furthermore, peaks 4, 7, 8, 9, and 10 were identified as uracil, uridine, adenine, guanosine, and adenosine, respectively.
Protozoa are unable to synthesize purines or pyrimidines, but can incorporate free adenine, guanine and uracil into their nucleic acids.
Gum Arabic (Acacia senegal L.) GA and adenine were both obtained from Sigma (St.
Epidemiology of Adenine Phosphoribosyltransferase Deficiency
After 6 weeks of treatment, the calcium in the aorta increased significantly in groups of adenine diet and adenine diet with quercetin supplementation compared with the control group, whereas the calcium in the aorta of the adenine diet with quercetin supplementation group was significantly lower than that in the adenine diet group (Figure 1(a)).
The compounds thymine (T), adenine (A), uracil(U), cytosine (C)guanine (G) 99% purity were purchased from sigma Chemicals Co.
To examine the subculture time, explants were subcultured to fresh MS medium supplemented with 1.0 mg/L 6-benzylaminopurine (BAP) and 70 mg/L adenine sulfate on an interval of 4, 6, and 8 weeks.
Adenine (dissolved in normal saline before use) was purchased from Amresco Inc (Solon, OH, USA).
Thymine, adenine, citric acid, potassium hydroxide, dichloromethane, diethyl ether, triethylamine, [alpha]-cyclodextrin, dimethylformamide, tosyl chloride, and fluorescein were purchased from Merck (Germany).
Because, adenine nucleotides and nucleosides (and ADA itself) may be released from activated inflammatory cells [22], as well as from neighbouring neuronal and nonneuronal enteric cells [23, 24], there is an increasing interest in the neuromodulatory effects exerted by adenosine during inflammatory insults.
It is obtainable by combining at least one of collagen and a derivative thereof; at least one of chitosan and an acetyl derivative thereof with a degree of acetylation of up to about 50%; at least one of a glycosylaminoglycan and a derivative thereof; and at least 10 substances selected from amino acids, [alpha]-biotin, (NH4)6Mo7024, adenine, A103, biotin, CaC12, calcium pantothenate, choline chloride, CoC12, CrK(SO4)2, CuSO4, D-Ca pantothenate, EDTA.Na2, EDTA.