adherens junction


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adherens junction

[ad′hir·enz jəŋk·shən]
(cell and molecular biology)
An integrin-mediated anchoring junction that connects the cytoskeleton (actin filaments) of a cell to the extracellular matrix or to the cytoskeleton of surrounding cells.
References in periodicals archive ?
The topics include the integration of cadherin adhesion and cytoskeleton at adherens junction, making connections: guidance cues and receptors at non-neural cell-cell-junctions, tuning collective cell migration by cell-cell junction regulation, beyond cell-cell adhesion: sensational cadherins for hearing and balance, and the loss of E-cadherin-dependent cell-cell adhesion and the development and progression of cancer.
In addition, [beta]-catenin is a critical component of the cadherin-mediated cell adherens junction.
Neither tight, septate, nor gap junctions are evident, leaving only the adherens junction to control the permeability of the epithelium.
Vascular endothelial- (VE-) cadherin and its associated catenins are important to form adherens junction complexes for controlling endothelial cell-cell adhesion.
Disruption of these adherens junction proteins or the actomyosin network that supports them either prevented the formation of the bi-layer, or caused a loss of pre-formed bi-layers.
Deconvolution combined with digital celocalization analysis to study the spatial distribution of tight and adherens junction proteins.
To date, a Hydra ortholog of ZO-1, a tight junction (TJ) and adherens junction (AJ) component in other organisms, has been isolated and localized to the apical margin of epithelial cells in the Hydra polyp (Fei et al.
Regulation of Sertoli-germ cell adherens junction dynamics in the testis via the nitric oxide synthase (NOS)/cGMP/protein kinase G (PRKG)/[beta]-catenin (CATNB) signaling pathway: An in vitro and in vivo study," Biology of Reproduction 73(3): 458-471.
Protein kinases and adherens junction dynamics in the seminiferous epithelium of the rat testis," Journal of Cellular Physiology 202(2): 344-360.
Adherens junction components, such as [Alpha]-catenin and E-cadherin, coassembled into these structures, along with desmosomal components and DP-NTP.
Ectoplasmic specialization, a testis-specific cell-cell actin-based adherens junction type: Is this a potential target for male contraceptive development?
Fer kinase/Fer T and adherens junction dynamics in the testis: An in vitro and in vivo study," Biology of Reproduction 69(2): 656-672.