adoptive immunotherapy

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Related to adoptive transfer: Flow cytometry, transgenic

adoptive immunotherapy

[ə¦däp·tiv ‚im·yə·nō′ther·ə·pē]
(immunology)
The transfer of immunologically competent white blood cells or their precursors into the host.
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Caption: Figure 2: Alloantigen immune tolerance is transferable by adoptive transfer of CD4+ T cells from long-lasting tolerant mice.
For both adoptive transfer systems, at 36 hr posttransfer, cells from blood, peripheral lymph nodes, and spleen were harvested from a subset of recipients, and the remainder of recipients were infected with IAV.
One implication is that future immune-based therapies for cancers and other diseases might get effective results from adoptive transfer of small numbers of individual T cells.
Induction of Tolerance by Adoptive Transfer of Treg Cells.
To address the possibility that C-Med 100[R] would influence the peripheral survival of lymphocytes, we performed adoptive transfer experiments.
A novel two-step process called adoptive transfer resulted in more than 50% tumor shrinkage in 6 of 13 patients with malignant melanoma, said Dr.
Adoptive transfer of splenic lymphocytes from immunized animals protected suckling mice against murine rotavirus-induced gastroenteritis in the absence of rotavirus-specific neutralizing antibodies, indicating that antigen-specific CTLs protect against mucosal pathogens in the intestinal tract (32).
Adoptive transfer of immune T cells also conferred protection in the challenge model whereas passive transfer of immune serum did not, indicating the critical role for T cell responses in control of this infection.
In addition, survival of skin allografts was prolonged after adoptive transfer of MDSC from ILT2 transgenic mice and histologic evaluation of the allografts, showing that MDSCs from ILT-2 transgenic mice were recruited to the graft.
5) promptly inform the Employer of the transfer of the animal up for adoption and adoptive transfer a copy of the contract if the party is a resident of the municipality Graces;
Optimal binding strength is believed to be the most important predictor of success in adoptive transfer therapies.