corticosteroid

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Related to adrenal steroids: ACTH, Corticosteroids

corticosteroid

[¦kȯrd·ə‚kō′stir‚ȯid]
(biochemistry)
Any steroid hormone secreted by the adrenal cortex of vertebrates.
Any steroid with properties of an adrenal cortex steroid.
References in periodicals archive ?
We measured 15 adrenal steroids simultaneously by LCMS/MS, including aldosterone, cortisol, 18-oxocortisol, 18-hydroxycortisol, cortisone, 11-deoxycortisol, 21deoxycortisol, corticosterone, 11-deoxycorticosterone, progesterone, 17-hydroxyprogesterone, pregnenolone, androstenedione, dehydroepiandrosterone (DHEA), and DHEA-sulfate (DHEA-S).
Adrenal Steroid Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Pregnanediol H H H H L 0 Androsterone H H H H L 0 Etiocholalone H H H N N 0 DHEA H H N L N 0 Pregnanetriol H H N L N 0 11-Ketoandrosterone H H N L N 0 11-ketoetiocholalone H N L L L 0 11-OH-androsterone H L L N L 0 * Case 1:54-yr-old woman hypertension, diverticulitis, palpitations, and severe Katribarelated stress.
Hollis-Eden Pharmaceuticals, a development-stage pharmaceutical company, is engaged in the development of a class of adrenal steroids for a broad array of potential indications.
A sensitivity analysis indicated the parameter uncertainties and identified transport and metabolic processes that most influenced the concentrations of primary adrenal steroids, aldosterone and Cortisol.
is developing a proprietary new class of small molecule compounds that are metabolites or synthetic analogs of adrenal steroid hormones.
Normal levels of circulating adrenal steroids appear to be necessary for accurate performance on spatial tasks, which is not surprising given the role of the hippocampus in spatial learning and memory.
The results presented today support the concept that it is possible to develop a targeted therapy to block HRPC-associated tumors by interrupting their ability to use adrenal steroids as growth factors.
Various adrenal steroids have been measured as markers of control, but the 3 most commonly used are 17OHP, androstenedione, and testosterone.
Through years of research with these compounds -- metabolic conversions or synthetic analogs of adrenal steroid hormones -- Hollis-Eden has made significant discoveries relating to their metabolism, mechanism of action and pharmacologic profile.
After the commencement of World War II, federal funding of adrenal steroid research quickly waned but Merck continued their collaboration with Kendall and Hench.
To exclude a deficiency of one of the enzymes in the pathway of steroid biosynthesis as a cause, the samples were tested for adrenal steroids (27).
Testing for adrenal steroids is also useful for differential diagnosis of polycystic ovary syndrome and nonclassic forms of CAH, which may sometimes be indistinguishable by clinical presentation and sonography (6).