agglutinogen

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agglutinogen

[ə‚glü′tin·ə·jən]

(immunology)

An antigen that stimulates production of a specific antibody (agglutinin) when introduced into an animal body.

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References in periodicals archive ?

which contains a four antigen acellular pertussis component: agglutinogens (FIM), pertactin (PRN), filamentous hemagglutinin (FHA), and pertussis toxin (PT).

Wyeth-Lederle Vaccines and Pediatrics

Potential vaccine-target antigens important in disease production include (1) tracheal cytotoxin that destroys cilia, making it difficult to clear thickened mucus; (2) pertussis toxin (lymphocytosis-promoting factor), which interferes with immune-cell function, contributes to ciliary damage, and aids in attachment to respiratory epithelium; (3) filamentous hemagglutinin, which helps the bacteria attach to cilia of the respiratory tract; (4) pertactin (69-kd protein), which also enhances bacterial attachment to cilia; and (5) agglutinogens, which may aid persistent attachment to cilia.

Routine vaccines across the life span, 2005

These include: 1) tracheal cytotoxin that destroys cilia, making it difficult to clear thickened mucus; 2) pertussis toxin (also called lymphocytosis-promoting factor), which interferes with immune cell function, contributes to ciliary damage, and aids attachment to respiratory epithelium; 3) filamentous hemagglutinin, which helps the bacteria attach to cilia of the respiratory tract; 4) pertactin (also called 69 kilodalton protein), which also aids bacterial attachment to cilia; and 5) agglutinogens, which may aid persistent attachment to cilia.