com)-- Gilad&Gilad LLC has served a Cease and Desist Letter to a dietary supplement marketer for alleged patent infringements upon Gilad&Gilad's agmatine
patents covering methods of use.
A homologof the gene encoding agmatine
deiminase, AgDI, which mediates acid tolerance in L.
The most common biogenic amines found in foods are histamine, tyramine, cadaverine, 2-phenylethylamine, spermine, sperm idi ne, putrescine, tryptamine, and agmatine
Neuroprotective effects of agmatine
against cell damage caused by glucocorticoids in cultured rat hippocampal neurons.
Chemicals and Pharmaceuticals II-26 Material Production and Production Testing II-27 Provides Information on Resin Acid Content II-27 Detection of 'NO' on Mineral Fibers II-27 GC-MS for Determining Monosaccharide Composition of Glycoprotein II-27 Alternative Method for Sampling and Simultaneous Analysis of Phenol, o-, m- and p-cresol II-27 Determination of Hexahydrophtalic Anhydride (HHPA) II-27 Detection and Quantitation of Agmatine
II-27 Determination of Plasma Aspirin and Salicylate II-27 Determination of Pheromone Stereochemistry II-28 Analysis of Calcium Channel Blocking Dihydropyridines II-28 To Determine Steroid Hormones II-28 Characterization of Rubbers, Polymers II-28 B.
The endogenously occurring analogues of L-arginine such as methyl-L-arginine, dimethyl-L-arginine and agmatine
which are normally present in the nervous tissue, have been found to inactivate both nNOS and eNOS and to decrease NO production in the brain (1).
NMDA receptor antagonists), including MK-801, eliprodil, agmatine
, and memantine, during the withdrawal period can protect against neuropathology and behavioral deficits associated with developmental alcohol exposure (Lewis et al.
In fact Arg is required for the synthesis of several compounds, such as ornithine, polyamines, proline, creatine, proteins, nitric oxide (NO), and citrulline, besides glutamate and agmatine
Arginine is a basic amino acid and serves as an essential precursor for the synthesis of biologically important molecules such as protein, ornithine, proline, polyamines, creatinine, nitric oxide and agmatine
(Wu and Morris, 1998).
One study on amphibians stained activated olfactory neurons with agmatine
and found no difference in the stimulation of olfactory neurons between atrazine-treated and control animals (Lanzel 2008).
Effects of NG-nitro-L-arginine methyl ester, 7-nitro indazole, and agmatine
on pentylenetetrazol-induced discriminative stimulus in Long-Evans rats Prog Neuropsychopharmacol Biol Psychiatry 2002; 26:567-73.
14) Additional branches of arg metabolism are mediated by: (a) nitric oxide synthases (NOSs) leading to production of nitric oxide (NO) and downstream nitrogenous compounds, (b) arg decarboxylase leading to agmatine
and its related byproducts, and (c) arg:glycine amidinotransferase leading to guanidinoacetic acid, the immediate precursor of creatine.