agonist


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Related to agonist: Agonist muscle, Dopamine agonist

agonist

[′ag·ə‚nist]
(biochemistry)
A chemical substance that can combine with a cell receptor and cause a reaction or create an active site.
(physiology)
A contracting muscle that is resisted or counteracted by another muscle, called an antagonist, with which it is paired.
References in periodicals archive ?
In aggressive tumour models, the NanoZolid technology enabled a controlled release of a STING agonist intratumorally.
Although different GnRH agonists have been used in GnRH antagonist cycles for the final oocyte maturation in high-responders, no universal consensus has been defined regarding the optimal agonist kind and dose, and there is no report evaluating the impact of different agonists on cycle outcomes.
The acceptance of the IND marks an important step in exploring this unique TLR 7/8 agonist intratumoral immunotherapy approach in solid tumors.
The authors noted that subjects who had undergone opioid agonist detoxification had a higher incidence of HCV infection than those who had undergone no treatment.
In a historically controlled prospective study on poor responders treated with classic flstu-up GnRH agonist regimen Karande et al.
Figure 3A,B shows results for agonist and antagonist mode, respectively.
This study ("Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells"), describes a unique approach to the development of GPCR-targeted therapeutics using Anchor's proprietary pepducin technology.
Based on its initial findings, the FDA is advising health care professionals to be aware of these potential risks and to weigh the benefits and risks of GnRH agonists when determining a treatment for patients with prostate cancer.
Larger epidemiologic studies in these other populations are needed to examine the possible relationships between dopamine agonist treatment, other clinical features and impulse control disorders," they concluded.
Adolor and Pfizer Inc (NYSE:PFE) are collaborating on the worldwide development and commercialization of two novel Delta opioid agonist compounds, ADL5859 and ADL5747, for the treatment of pain.
Furthermore, we look forward to working closely with Merck's world-class chemists to expand our portfolio of novel TLR 7 and TLR 8 agonist compounds.