Synthesis and characterization of 2,4 dihydroxy substituted chalcones using aldol
condensation by SO[Cl.sub.2]/EtOH.
List, "Quantum mechanical predictions of the stereoselectivities of proline-catalyzed asymmetric intermolecular aldol
reactions," Journal of the American Chemical Society, vol.
Polymeric enzymes analogues are used in many reactions such as hydrolysis reactions, Diels-Alder aldol
condensation, isomerization, and stereoselective reactions, and regioselective reactions [3, 5, 8,18-20].
Excess glucose enters the polyol pathway and activates aldol
reductase (AR) but because sorbitol dehydrogenase (SDH) activity does not increase similarly, sorbitol accumulates.
Reactions employed in the synthesis include Nucleophilic Aromatic Substitution (NAS), Aldol
Condensation, and SN2 Substitution.
Among their topics are cycloaddition reactions, sigmatropic rearrangements and related processes promoted by silver, silver(I)-mediated electrocyclic processes, cycloisomerization reactions catalyzed by silver, silver carbenoids, aldol
and related processes, coupling reactions promoted by silver, the supramolecular chemistry of silver, and a critical comparison of the three coinage metals.
Simultaneously, glutaraldehyde reacts with itself (aldol
synthesis) resulting in aldol
reactions catalyzed by tryptophan in water.
Key steps included a diisopinocampheylchloroborane (DPC)-catalysed aldol
reaction that was shown to be highly sensitive to traces of moisture.
Khilevich A, Aye M, Flavin MT, Rizzo JD, Lin L, Dzekhtser S, Brankovic D, Zhang H, Chen W, Liao S, Zembower DE, Xu ZQ (1996) Synthesis of (+)-calanolide A, an anti-HIV agent, via enzyme-catalyzed resolution of the aldol