The genetic basis of primary aldosteronism
. Curr Hypertens Rep.
Also, be aware of the results of any lab testing, particularly your kidney function or low potassium levels, which might signal primary aldosteronism
Aldosterone/renin ratio is an effective screening test for primary aldosteronism
having a high negative predictive value17.
(1991) Aldosterone synthase cytochrome P450 expressed in the adrenals of patients with primary aldosteronism
on the affected side(s) was diagnosed if there was early visualization of the tracer before the fifth postinjection day and if intense uptake (greater than that seen in the liver) was noted on the image .
Intralymphocyte free magnesium in patients with primary Aldosteronism
. Hypertension 1999; 35: 113-117.
The producer of clinical instruments and diagnostic testing kits released details of the launch of a new product designed to detect primary aldosteronism
, a condition linked to cardiovascular illnesses, which received a positive diagnosis from investors.
Those include a chimeric mutation of the 11b-hydroxylase/aldosterone synthase genes (glucocorticoid-remedial aldosteronism
), a b-subunit mutation of the amiloride-sensitive epithelial sodium channel (Liddle's syndrome), and deletion and mis-sense mutations in the WNK family of serine-threonine kinases (pseuhypoaldosteronism type 2).
Examples are chronic renal failure and renal artery stenosis, primary aldosteronism
and the use of oral contraceptives.
can lead to electrolyte abnormalities that may produce mental status changes.
The patients meeting the following criteria were excluded from the study: renal artery stenosis, coarctation of the aorta, pheochromocytoma, primary aldosteronism
, Cushings's syndrome, renal disease, and increased dietary-sodium intake/drugs, or those that were taking drugs that interfere with uric acid levels and/or those with a history of gout or renal stones.
Vongpatanasin and her team studied 14 hypertensive patients who overproduced aldosterone, a condition known as primary aldosteronism
. The researchers then compared them with 20 hypertensive patients and 18 patients with normal blood pressure.