alkaline phosphatase


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alkaline phosphatase

[′al·kə‚līn ′fäs·fə‚tās]
(biochemistry)
A phosphatase active in alkaline media.
References in periodicals archive ?
DALLAS -- Primary biliary cirrhosis can be reliably diagnosed without performing a liver biopsy in patients with antimitochondrial antibodies and elevated alkaline phosphatase levels, Dr.
Diagnostic aspects of alkaline phosphatase and its isoenzymes.
Moreover, each assay has an inbuilt negative control of dim CD11b-positive/CD 14-ncgative lymphocytes, which lack expression of alkaline phosphatase.
Interpretation and clinical significance of alkaline phosphatase isoenzyme patterns.
Several techniques that have been developed to differentiate the bone and liver isoenzymes have improved the specificity and sensitivity of alkaline phosphatase tests.
This allows streamlining of the restriction enzyme digestion, desphosphorlyation and ligation procedure by eliminating the need of cleanup after alkaline phosphatase treatment.
Affected individuals have low levels of the tissue non-specific form of alkaline phosphatase, an essential regulator of bone mineralization, leading to rickets in infants and children and osteomalacia ("soft bones" resulting from poor mineralization) in adults.
In addition, a greater majority of the patients who received zoledronic acid achieved normalized alkaline phosphatase levels at 6 months compared with those who received risendronate (88.
Patients suffering from chronic renal dysfunction are monitored by measurement of biochemical markers such as serum total alkaline phosphatase (ALP) to detect increased bone remodeling before the development of advanced renal osteodystrophy.
9]/L, serum albumin 20 g/L, bilirubin 17 [micro]mol/L, alkaline phosphatase 132 U/L, alanine transaminase 16 U/L, and aspartate transaminase 23 U/L.
Several serum markers, including maternal serum APP, alkaline phosphatase, granulocyte colony-stimulating factor, ferritin, and interleukin-6, were measured in those women and in 111 matched controls.
Pharmacokinetics and pharmacodynamics were measured for growth hormone, insulin-like growth factor-1 (IGF-1), and bone alkaline phosphatase (BAP) using samples taken following the first and third subcutaneous injections.

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