alkylate

(redirected from alkylating)
Also found in: Dictionary, Medical.

alkylate

[′al·kə‚lāt]
(organic chemistry)
A product of the alkylation process in petroleum refining.
References in periodicals archive ?
The purine-like structure of these reductive alkylating agents may permit selective inactivation of purine-utilizing enzymes in low reduction potential tumor cells.
Three small, nonrandomized studies using historical controls suggest some protective effect in patients getting GnRH before alkylating chemotherapy for Hodgkin's disease and non-Hodgkin's lymphoma.
TEMODAL (temozolomide) Capsule is an oral, cytotoxic alkylating agent indicated for treating glioblastoma multiforme (GBM).
At one TRC member institution, the Massachusetts Institute of Technology (MIT), researchers are focusing their attention on the effects of simple and complex alkylating agents, a class of DNA-damaging environmental toxins and toxicants that cause cell death, mutations, birth defects, and cancer.
Cisplatin falls into the category of chemotherapy agents called alkylating agents.
The anti-neoplastic agent can be an alkylating agent, an antibiotic agent, an antimetabolic agent, a retinoid, a hormonal agent, a plant-derived agent, an anti-angiogenesis agent and a biologic agent such as monoclonal antibody and interferon.
Minnetonka, MN, worldwide rights to Busulfex Injection, an intravenous formulation of the alkylating agent busulfan, a drug often used in bone marrow transplantation.
Ovarian damage may occur after high doses of abdominopelvic radiation and/ or alkylating agent (cyclophosphamide, ifosfamide, mustard/procarbazine) chemotherapy are given.
A humanized monoclonal antibody for treating B-cell chronic lymphocytic leukemia in people who have been treated with alkylating agents and have failed treatment with fludarabine.
b) A derivative [Hcy-acetylbenzoic acid (Hcy-ABA)] is formed by reacting with the alkylating agent p-(2-chloroacetyl)benzoic acid phosphate (CABA-phosphate); and
He and a team of researchers have developed a way to measure the ability of particular cancer cells to repair the damage done to DNA by a category of commonly utilized anti-cancer drugs that are known as alkylating agents, including nitrosourea and cisplatinin.
Alkylating and non-alkylating compounds interacting with the DNA minor groove.