alloantibody

(redirected from alloantibodies)
Also found in: Dictionary, Thesaurus, Medical.
Related to alloantibodies: alloantigen

alloantibody

[¦a·lō¦ant·i‚bäd·ē]
(immunology)
Antibody that reacts with an antigen occurring in a genetically different member of the same species.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The data obtained from recipients included the most recent creatinine level (mg/dl), peak creatinine (mg/dl), viral load of polyomavirus (DNA copies/ml), and the quantization of alloantibodies, pre- and post-transplant.
[6] Consequent to the introduction of routine RhIG immunoprophylaxis, alloantibodies other than anti D have emerged as an important cause of HDFN and now responsible for greater proportion of these cases.
When patients develop rare or multiple alloantibodies, molecular techniques, such as genotyping, may be required.
Pretransfusion blood samples from all SCD patients were tested for the presence of alloantibodies by gel technology using commercial 3-cell panel (Diacell, Diamed ID, Switzerland), with polyspecific (anti-IgG + C3d) anti-human globulin (AHG) and homozygous expression of the antigens.
Alloantibodies recognize antigenic epitopes displayed by HLA molecules on the transplanted allograft through complement-dependent and independent pathways [89].
The technique: Lymphocytes are tested with a panel of sera containing well-characterized HLA-specific alloantibodies. Each serum is placed in a microtiter well of a Terasaki plate (60-72 wells/plate).
However, although all canine blood group antigens can stimulate the formation of alloantibodies, DEA 1 seems to be the most immunogenic and also is considered the most clinically important.
Hendrickson, "Clinically significant anti-KEL RBC alloantibodies are transferred by breast milk in a murine model," Vox Sanguinis, vol.
Our data may explain previously published data, where MSC-[gamma] infused mice had higher levels of circulating anti-donor IgM and IgG alloantibodies, which resulted in the rapid induction of antibody-mediated rejection [44].
Blumenberg, "Management of bleeding in a multi-transfused patient with positive HLA class I alloantibodies and thrombocytopenia associated with platelet dysfunction refractory to transfusion of cross-matched platelets," Blood Coagulation and Fibrinolysis, vol.