alloantibody


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Related to alloantibody: alloantigen

alloantibody

[¦a·lō¦ant·i‚bäd·ē]
(immunology)
Antibody that reacts with an antigen occurring in a genetically different member of the same species.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Of the 125 recipients for whom alloantibody data were available, 46.2% had developed de novo post-transplant donor-specific alloantibodies, and 19.5% had had pre-existing and post-transplant alloantibodies.
The addition of rare or new alloantibody formation to a hemolytic transfusion reaction, such as HS, can increase the complexity of treatment and may require specialized blood products.
Our results showed that the majority of SCD patients had a single alloantibody rather than multiple alloantibodies.
The risk of alloantibody production and transfusion reactions against antigens other than DEA 1 is not yet well defined [2] and there is no documented clinical evidence of a hemolytic reaction caused by DEA 1.2, 3, 5, and 7 in mismatched transfusions [18].
Platelet transfusion refractoriness associated with HPA-1a (PlA1) alloantibody without coexistent HLA antibodies successfully treated with antigen-negative platelet transfusions.
Qualitative variables in this study such as gender blood group presence or absence of alloantibody and autoantibodies were expressed in terms of frequencies and percentages and presented as frequency distribution tables.
Sachs et al., "Long-term outcome and alloantibody production in a non-myeloablative region for induction of renal allograft tolerance," Transplantation, vol.
IT can also be caused occasionally by the presence of a donor origin autoantibody [10] or by the presence of a recipient-origin alloantibody against a donor platelet alloantigen.
Further laboratory results (direct antiglobulin test and bilirubin) were assessed and reported for five babies whose maternal alloantibody titre by IAT tube was less than 16, but equal to 16 by CAT.
Immunotoxicity testing showed that there was no treatment-induced alloantibody formation or induction of autoimmunity.
Maternal anti-K is the second most common alloantibody (anti-D is the first) and accounts for 10%45% of all patients with antibody-mediated severe hemolytic anemia (2).