alloantibody


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Related to alloantibody: alloantigen

alloantibody

[¦a·lō¦ant·i‚bäd·ē]
(immunology)
Antibody that reacts with an antigen occurring in a genetically different member of the same species.
References in periodicals archive ?
Qualitative variables in this study such as gender blood group presence or absence of alloantibody and autoantibodies were expressed in terms of frequencies and percentages and presented as frequency distribution tables.
This model was used to test 1) if the difference between the 2 methods was significant; 2) if the observed differences were significantly different for each alloantibody; and 3) if the observed differences for any alloantibody type were different to the combination of the others.
The transfusion of matched red cell units can prevent alloantibody formation.
Red blood cell alloantibody frequency, specificity and properties in a population of male military veterans.
High-throughput DNA typing could facilitate support for patients undergoing long-term transfusion who are at high risk of alloantibody production, such as patients with sickle cell disease, thalassemia, or autoimmune hemolytic anemia.
A panreactive autoantibody can mask an existing alloantibody by making all donor units appear cross-match incompatible.
CLSI guideline, "Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Approved Guideline," describes criteria for optimizing flow cytometry cross matching and the detection of human leukocyte antigen (HLA) alloantibody by solid phase methods in conventional and multiplex platforms.
Because these recently transfused patients have a chimera of donor and recipient cells, an autologous adsorption may actually remove a clinically significant alloantibody which may be reacting only with donor cells.
CLSI has also published a new document, Detection of HLA-Specific Alloantibody by Flow Cytometry and Solid Phase Assays; Approved Guideline (I/LA29-A), which describes criteria for optimizing flow cytometry crossmatching and the detection of human leukocyte antigen (HLA) alloantibody by solid-phase methods in conventional and multiplex platforms.
and the plasma obtained was used to perform alloantibody screening by using commercially available 3-cell panel (Diacell, Bio-Rad, Switzerland).
The panagglutinating antibody may mask a coexisting alloantibody and place the patient at increased risk for a hemolytic transfusion reaction.
Evaluation of polyethylene terephthalate for ABO and Rh typing and alloantibody screening.