allosteric site


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allosteric site

[¦a·lə¦ster·ik ′sīt]
(biochemistry)
The inactive (or less active) region of an enzyme molecule.
References in periodicals archive ?
137) It is reasonable to assume that allosteric modulators and allosteric activators are subtype-specific because allosteric sites are not the sites of physiological ligands and thus are not conserved, in contrast with the orthosteric site.
The Ii-Key motif from the Ii protein acts at an allosteric site adjacent to the MHC class II antigenic peptide-binding trough to enhance presentation of covalently linked epitopes 200-500 times in vitro.