alloxan


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Related to alloxan: streptozotocin

alloxan

[ə′läk·sən]
(biochemistry)
C4H2N2O4 Crystalline oxidation product of uric acid; induces diabetes experimentally by selective destruction of pancreatic beta cells. Also known as mesoxyalyurea.
References in periodicals archive ?
Alloxan induced diabetes caused an elevation of lipid peroxidation, cholesterol and triglyceride concentrations, but resulted in a decrease in catalase activity in the liver and kidney of female and male rats.
Inhibition of glucokinase and hexokinase from pancreatic B-cells and liver by alloxan, alloxantin, dialuric acid, and t-butylhydroperoxide.
2002, "Effect of Terminalia arjuna on the antioxidant defense system in alloxan induced diabetes in rats," Biomedicine, 22, pp.
Regeneration of beta cells in islets of Langerhans of pancreas of alloxan diabetic rats by acetone extract of Momordica charantina (Linn.
Dixit et al (1986) treated both normoglycemic and alloxan induced hyperglycemic rats with neem oil at a dose of 200 mg/kg orally.
Studies are being developed which will investigate rodent pancreatic islet cell free radical formation induced by alloxan monohydrate.
Immunoassay of pancreatic and plasma insulin following alloxan injection of rats.
Its hypoglycemic activity is in agreement with the reported antidiabetic activity of TLFA in alloxan diabetic mice and rats.
in a study done on rats with diabetes caused by Alloxan show that hyperglycemia cause reduction in cu+2 level which is an important co-factor for superoxidase dismutase.
Hyperglycaemia was induced in the mice by three doses of alloxan.