macroglobulin

(redirected from alpha2-macroglobulin)
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macroglobulin

[¦mak·rə′gläb·yə·lən]
(biochemistry)
Any gamma globulin with a sedimentation constant of 195.
References in periodicals archive ?
Chodorowska G, Wojnowska D, Juszkiewicz-Borowiec M: C-reac-tive protein and alpha2-macroglobulin plasma activity in medium-severe and severe psoriasis.
Alpha2-macroglobulin (AMG) is similar to AAT and most other proteinase inhibitors, except that it is a very large molecule, approximately 750 kD as compared, for example, to antithromin III (only 65 kD).
Increased immunogenicity of HIV envelope subunit complexed with alpha2-macroglobulin when combined with monophosphoryl lipid A and GM-CSF.
They are believed to act by inhibiting fibroblast growth and decreasing alpha2-macroglobulin levels, leading to collagen degradation.