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1. Pathol any substance that passes into and accumulates within cells, tissues, or organs
2. Pathol a local anaesthetic solution injected into the tissues to cause local anaesthesia
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
The following article is from The Great Soviet Encyclopedia (1979). It might be outdated or ideologically biased.



an accumulation in bodily tissues of cellular elements admixed with blood and lymph. Inflammatory and tumorous infiltrates occur most often.

An inflammatory infiltrate consists chiefly of polymorphonuclear leukocytes (suppurative infiltrate), erythrocytes (hemorrhagic infiltrate), lymphoid cells (round cell infiltrate), and histiocytes and plasma cells (histiocyte-plasma cell infiltrate). These infiltrates may be resolved, may liquefy, or may undergo sclerosis and form caverns, abscesses, scars, and so forth.

A tumorous infiltrate consists of tumor cells of different kinds (carcinoma, sarcoma); it is a manifestation of the infiltrating growth of a tumor. When an infiltrate forms, the tissue enlarges, changes color, and becomes harder and sometimes painful. In surgical practice, an infiltrate is an induration that develops in tissues when they become saturated with an anesthetic.


The Great Soviet Encyclopedia, 3rd Edition (1970-1979). © 2010 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
Soon afterwards, he was admitted to the ICU with respiratory insufficiency and signs of bilateral alveolar infiltrates on chest X-ray.
Chest X-ray on admission showed bilateral alveolar infiltrates. Enterobacter aerogenes and Enterococcus faecalis were isolated from a bronchus aspirate on admission.
(1) He had the Rapid onset of respiratory distress, diffuse crackles on lung examination, bilateral, confluent alveolar infiltrates on chest roentgenogram and progressive arterial hypoxemia refractory to supplemental oxygen therapy.
A diagnosis of DAH should be entertained only when a patient presents with diffuse alveolar infiltrates. Diffuse alveolar hemorrhage may occur with or without associated capillaritis; however, it is typically the cases with capillaritis that may present with clinical manifestations of ALI.
Computed tomography (CT) scan of his chest showed multiple pulmonary nodules and alveolar infiltrates with small cavities suggestive of septic infarctions.
Of note on the chest radiograph were right upper lobe alveolar infiltrates.
All hallmarks of the most severe form of acute lung injury, the acute respiratory distress syndrome (ARDS) are present: dyspnoea, refractory hypoxaemia, an inflammatory response, reduced pulmonary compliance and diffuse alveolar infiltrates on chest radiography (2).
The classic chest radiograph reveals bilateral, diffuse alveolar infiltrates consistent with alveolar flooding The absence of cardiomegaly and pleural effusion radiographically distinguishes ARDS from cardiogenic pulmonary edema.
A chest radiograph showed bilateral alveolar infiltrates. A pulmonary arteriograph showed no evidence of pulmonary emboli.
A case was defined as occurring in a patient with bilateral alveolar infiltrates that required intubation and mechanical ventilation.
One week later, a chest radiograph showed bilateral alveolar infiltrates suggestive of pulmonary edema (Figure).
Radiographic changes exhibited at admission consisted of bilateral interstitial infiltrates in 14 patients (56%), alveolar infiltrates in 4 (16%), and mixed infiltrates in 5 (20%) patients.