melanoma

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Related to amelanotic melanoma: Nodular melanoma

melanoma:

see skin cancerskin cancer,
malignant tumor of the skin. The most common types of skin cancer are basal cell carcinoma, squamous cell carcinoma, and melanoma. Rarer forms include mycosis fungoides (a type of lymphoma) and Kaposi's sarcoma.
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Melanoma

melanoblastoma; a malignant tumor that consists of melanin-producing cells.

Factors conducive to the development of melanomas include injury and hormonal stimulation, especially during puberty. Melanomas generally occur on the skin; less often, they appear on the retina, pia mater, nasopharynx, larynx, esophagus, and mucosa of the intestine and other organs. Melanomas usually develop at the site of pigmented or depigmented birthmarks, but they may also appear elsewhere. The process starts with a barely perceptible, painless tumor on the skin, sometimes resembling a wart, which gradually becomes dark brown or black. Occasionally, it ulcerates and bleeds. In case of injury, the tumor may enlarge quickly and become tuberous, dense at the base, and stiffer. The regional lymph nodes enlarge. The initial signs that a melanoma is developing at the site of a birthmark are the birthmark’s enlargement, an intensification or reduction in its pigmentation, and the appearance of a red rim around it. Treatment involves prompt surgical intervention, based on early diagnosis, and the use of radiotherapy and drugs to retard the growth and reproduction of the cells.

I. IA. SHAKHTMEISTER

melanoma

[mel·ə′nō·mə]

(medicine)

A malignant tumor composed of anaplastic melanocytes.

A benign or malignant tumor composed of melanocytes.

melanoma

Pathol a malignant tumour composed of melanocytes, occurring esp in the skin, often as a result of excessive exposure to sunlight

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References in periodicals archive ?

The framework then allowed the immunohistochemical diagnosis of metastatic amelanotic melanoma.

Amelanotic melanoma with tonsillar and thyroidal metastases and no primaries detected

Development of cutaneus amelanotic melanoma in the absence of a functional tyrosinase.

Melanoma nodular amelanotico

Amelanotic melanoma may also be mistaken as a polyp if one is unaware of the entity.

Sinonasal mass--a diverse clinicopathological entity--an experience in a tertiary care centre in the north eastern India

An amelanotic melanoma appears similar to lymphoma, squamous cell carcinoma or other non-pigmented conditions, such as pyogenic granuloma, a conjunctival haematoma, a foreign body or argyrosis.

Conjunctival melanocytic lesions: referral refinement part 2: course code: C-16011 O/D

A potential clinical clue to the diagnosis of amelanotic melanoma may be the presence of a macular rim or spot of tan, gray, or brown pigmentation at the periphery of the lesion," Ms.

Nonpigmented melanoma mimicked benign lesion: 8% of cutaneous melanomas

In the case of amelanotic melanoma or large melanoma that has broken through BruclTs membrane, the double circulation sign is noted (Figure 6).

Uveal tract melanoma: referral refinement part 1 course code: C-15795 O/D

In fact, even in the absence of pigment, any "red and white" lesion could be an amelanotic melanoma.

An aid for spotting basal cell carcinoma: the "dark dot sign" can support a diagnosis of basal cell carcinoma or even suggest it when other findings are minimal

A case of a secondary amelanotic melanoma of the epiglottis was reported by Ikeda et al in 1991.

Primary malignant melanoma of the epiglottis: a rare presentation

The remaining four lesions included one amelanotic melanoma and three with none or only one of the ABC criteria.

It's time to update melanoma screening criteria: the screening criteria known as ABCD, introduced in 1985, are overdue for a revision, experts say

All clinically suspected pyogenic granulomas must be biopsied to rule out other conditions, such as irritational fibroma, hemangioma, Kaposi's sarcoma, leiomyoma, amelanotic melanoma, basal metastatic carcinoma, and squamous cell carcinoma.

Extragingival pyogenic granuloma in an elderly female: a case report

Epithelioid sarcomas are sometimes composed of spindle-shaped cells, and they may be confused with other malignant spindle-cell neoplasms, such as synovial sarcomas, fibrosarcomas, angiosarcomas, malignant fibrous histiocytomas, malignant extrarenal rhabdoid tumor, epithelioid hemangioendothelioma, and amelanotic melanoma.

Epithelioid sarcoma

Depending on the patient's age and the location of the tumor, the differential diagnosis includes malignant schwannoma, malignant fibrous histiocytoma, fibrosarcoma, amelanotic melanoma, malignant lymphoma, squamous cell carcinoma, extramedullary plasmacytoma, metastatic tumor, glandular tumor, chondroma, chondrosarcoma, osteogenic sarcoma, and inverted papilloma.