New classification of maxillary ameloblastic carcinoma based on an evidence-based literature review over the last 60 years.
Reconnoitre ameloblastic carcinoma: a prognostic update.
Ameloblastic carcinoma showing the pattern of ameloblastoma but also cytonuclear atypia, which allows for the distinction between the entities (hematoxylin-eosin, original magnification X400).
Area of necrosis in spindle cell-type ameloblastic carcinoma (hematoxylin-eosin, original magnification X150).
Slater has mentioned the term "spindle-shaped ameloblastic carcinoma" in 1999.
In genome analysis, the CpG methylation of p16 (cyclindependent kinase inhibitor 2A) is observed in all ameloblastic carcinoma samples, but only one ameloblastoma specimen exhibits the mutation.
Muller, "Malignant ameloblastoma or ameloblastic carcinoma," Oral Surgery, Oral Medicine, Oral Pathology, vol.
Hartman, "Ameloblastic carcinoma: a clinicopathologic study and assessment of eight cases," Oral Surgery, Oral Medicine, Oral Pathology, vol.
Ameloblastic carcinoma is defined as a malignant epithelial odontogenic tumour that histologically has retained the features of ameloblastic differentiation yet also exhibits cytological features of malignancy.
Ameloblastic carcinoma mainly affects elderly individuals, but the age range is 15 to 84 years.
Histomorphologically, two different Ameloblastic carcinoma entities may be recognized.
Radiographically Ameloblastic carcinoma can be radiolucent, either unilocular or multilocular, which generally has a honeycomb appearance with tooth root resorption.