amine oxidase


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to amine oxidase: Lysyl oxidase

amine oxidase

[ə′mēn ′äk·sə‚dās]
(biochemistry)
An enzyme that catalyzes the oxidation of tyramine and tryptamine to aldehyde.
References in periodicals archive ?
The report provides a snapshot of the global therapeutic landscape for Lysine-Specific Histone Demethylase 1A (Lysine (K)-Specific Demethylase 1 or Flavin-Containing Amine Oxidase Domain-Containing Protein 2 or EC 1.
The report reviews Lysine-Specific Histone Demethylase 1A (Lysine (K)-Specific Demethylase 1 or Flavin-Containing Amine Oxidase Domain-Containing Protein 2 or EC 1.
Tyramine hydrochloride, benzylamine hydrochloride, amine oxidase inhibitors, quercetin, trans-resveratrol, and other reagents were obtained from Sigma-Aldrich (Saint-Quentin-Fallavier, France), except otherwise specified.
However, resveratrol and other phenolic compounds altered the consequences of amine oxidase activities that rely on hydrogen peroxide production in hAT, since they were impairing the insulin-like action of benzylamine on glucose uptake in adipocytes.
Tanizawa, Inhibition of copper amine oxidases by pyridine-derived aldoximes and ketoximes, Biochimie, 83, 995 (2001).
Some of the members of this class of cuproenzymes include Cu/Zn SOD (antioxidant defense), cytochrome C oxidase (mitochondrial respiration), CP (iron metabolism), tyrosinase (pigmentation), lysyl oxidase (collagen maturation in connective tissue), Hephaestin (intestinal iron efflux), dopamine [[beta]-hydroxylase (catecholamine synthesis), Peptidylglycine [alpha] -amidating monooxygenase (peptide-hormone processing), amine oxidase (removal of hormones), ascorbate oxidase and catalase oxidase (oxidation of primary alcohols to aldehydes) (44).
Pea seedlings amine oxidase (PSAO) has been found to have a 100% relative specific activity towards 1,4-diaminobutane, 111% towards 1,5-diaminopentane, 56% towards agmatine and spermidine, 44% towards 1,6-diaminohexane, 30% towards histamine, 8% towards spermine, and no activity towards 1,3-diaminopropane [13].
Studying a bovine amine oxidase, two independent research groups found clues that pyrroloquinoline quinone (PQQ) might be the enzyme's missing sidekick in cows -- and perhaps in humans as well, Klinman says.