When blood parameter changes were reviewed between the groups, preoperatively and postoperatively, no significant difference was found statistically regarding levels of urea or creatinine; AST (aspartate
aminotransferase); ALT (alanine
aminotransferase); or glomerular filtration rates (GFR) (p> 0.05) (Table-IV).
Table-IV: Sensitivity, specificity, positive predictive value, negative predictive value and diagnostic Accuracy of Aspartate
aminotransferase platelet ratio index(APRI) (n=135).
In 'Clinical Relevance and Discriminatory Value of Elevated Liver
Aminotransferase Levels for Dengue Severity' concluded that although
aminotransferase levels increased in conjunction with dengue severity, AST or ALT values did not discriminate between DF and DHF or non-severe and severe dengue.
A publication from the Mayo Clinic by Hay et al (3) in 1989, still just before the discovery of the hepatitis C virus, specifically focused on patients with unexplained chronic
aminotransferase elevations and no symptoms, but the biopsy findings were able to provide specific diagnoses in most of these patients.
Elevations of serum
aminotransferase in muscular dystrophy.
We then stratified
aminotransferase values according to VL classes, as both VL and
aminotransferases were monitored in 1,269 patients.
Compared to
aminotransferases, creatine kinase (CK) is a more specific index of muscle injury [20]; therefore, we hypothesized that CK-adjusted
aminotransferase levels may present an even more accurate biomarker of liver damage in dystrophinopathy.
Further therapy with 12 weekly pulses of IVMP in these patients with active GO can be considered, after
aminotransferase normalization, without a history of ALI and the presence of viral hepatitis.
Also, short term CPAP therapy doesn't seem have beneficial effects on serum
aminotransferase levels in patients of OSAS.
Overall improvement was observed in subsequent alanine
aminotransferase levels (491 units per litre, IQR 356.5 TO 775 vs 151 units per litre, IQR 49.5 to 299.5).
Several noninvasive methods such as aspartate
aminotransferase (AST)/alanine
aminotransferase (ALT) ratio (AAR), aspartate aminotransferase-to-platelet ratio index (APRI) [6], and fibrosis indexbased on the four factors (FIB-4) [7] have been used to assess disease severity.
On presentation, she was febrile and tachycardic with laboratory data significant for
aminotransferase elevation (ALT 998 U/L, AST 4559 U/L) and disseminated intravascular coagulopathy (DIC) (Figures 3 and 4).