amphotericin B


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Related to amphotericin B: liposomal amphotericin B

amphotericin B

(ăm'fətĕr`ĭsĭn), antibioticantibiotic,
any of a variety of substances, usually obtained from microorganisms, that inhibit the growth of or destroy certain other microorganisms. Types of Antibiotics
..... Click the link for more information.  that halts the growth of several disease-causing fungi. Discovered in 1956, it is produced by bacteria of the genus Streptomyces. It is used in lotion or ointment form to treat fungal infections of the skin and is given internally only to patients with potentially fatal fungal infections. Amphotericin B is not effective against bacterial infections.

amphotericin B

[‚am·fə′ter·ə·sən ′bē]
(microbiology)
C46H73O20N The active component of amphotericin, suitable for systemic therapy of deep or superficial mycotic infections.
References in periodicals archive ?
Six vials, each containing 50 mg of conventional non-lipid amphotericin B (Fungizone[R]), were available in each of the two ADCs in the ICU.
Alert: mix-ups between conventional and lipid formulations of amphotericin B can be extremely dangerous
Amphotericin B was used as the positive control in this experiment.
In vitro synergistic efficacy of combination of amphotericin B with Myrtus communis essential oil against clinical isolates of Candida albicans
The balance of evidence suggests that amphotericin B (0.
Treatment of HIV-associated cryptococcal meningitis in South Africa: the case for amphotericin B over conventional dose fluconazole for initial therapy
A clinical study comparing AmBisome to amphotericin B deoxycholate (Study 94-0-002) showed that AmBisome was well tolerated.
Gilead Sciences and World Health Organization Establish New Five-Year Initiative to Prevent Deaths from Visceral Leishmaniasis
Amphotericin B in Mic A, Mic B and FIC ranges between 0.
The inhibition of Candida species by selected essential oils and their synergism with Amphotericin B
For the 25-mg dose, the peak systemic level of the drug was 20 ng/mL, which is about 2% of the level generally regarded as the threshold of toxicity for amphotericin B, Dr.
Aerosol amphotericin B in the works as fungal prophylaxis
Because the most common fungal etiology of near drowning pneumonia is P boydii, an organism resistant to amphotericin B, bronchoscopy was performed to assess for a common pulmonary and cutaneous pathogen.
Pulmonary Pseudallescheria boydii infection with cutaneous zygomycosis after near drowning
In a study conducted by researchers at the National Cancer Institute, the urinary pharmacokinetics and disposition of Nyotran(R) (2, 4 or 6 mg/kg) and amphotericin B (1 mg/kg) were investigated in normal rabbits.
Aronex Pharmaceuticals Reports Phase II Data on Nyotran(R) in Patients With Invasive Aspergillus Infections
In each dose group, twelve volunteers received a single dose of Bioral Amphotericin B and four received a placebo.
BioDelivery Sciences Announces Initial Results of Phase 1 Clinical Study of Bioral Amphotericin B
Azotemia, hypokalemia, and normocytic anemia were observed as adverse effects of the previous amphotericin B treatment.
Human Pythiosis, Brazil
The changing epidermiology of fungal infections: Are the lipid-forms of amphotericin B an advance?
Cutaneous mucormycosis of the head and neck with parotid gland involvement: first report of a case
Successful treatment of aspergillosis in liver transplant recipients should include early diagnosis, sequential medical treatment with lipid amphotericin B and itraconazole, and surgical intervention for invasive disease.
Aspergillosis in liver transplant recipients: successful treatment and improved survival using a multistep approach
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