amyloid

(redirected from amyloid plaque)
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amyloid

[′am·ə‚lȯid]
(pathology)
An abnormal protein deposited in tissues, formed from the infiltration of an unknown substance, probably a carbohydrate.
References in periodicals archive ?
1, 2016, highlighted an academic article on "the antibody aducanumab" which reduces beta amyloid plaques in the brain.
We have determined that the G protein-coupled receptor 3, a protein which also found in the brain, is responsible for the production of amyloid-beta peptides and the aggregation of amyloid plaques," said Thorsson.
Exactly what causes the cells to die is not known, but many years before the first symptoms present themselves, pathological changes occur, such as the deposition of the protein amyloid in the form of amyloid plaques, the accumulation of tau proteins and inflammatory changes that eventually degrade the points of contact between neurons.
All had their brains scanned using a tracer chemical that binds with amyloid plaques so that they show up on the images.
Complete regression of amyloid plaques in middle aged mice and significant reduction of plaques in the cortex and hippocampus of old mice were reported at the end of the study.
Scientists have linked poor sleep with a build up of amyloid plaques - sticky clumps of protein that build up in the brain which are a hallmark of Alzheimer's disease.
PKC Isozymes Regulate Amyloid Plaque and Neurofibrillary Tangle Metabolism
The next step is to test curcumin on human amyloid plaque formation using newer brain scans and there are plans for that.
When AN-72 was given to mice their immune system attacked it and the amyloid plaque.
In preclinical studies, EVP-0962 has demonstrated a significant reduction in amyloid plaques, which are believed to be a cause of Alzheimer's disease, and reversed behavioral deficits.
Researchers found that the proposed link between caffeine and reductions in the beta amyloid plaque accumulation characteristic of Alzheimers disease (AD) suggest a possible role for caffeine in AD treatment.
The participants underwent brain scans to determine the levels of amyloid plaque in their brains and blood tests to measure their levels of LDL and HDL cholesterol.