amyloid

(redirected from amyloid plaque)
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amyloid

[′am·ə‚lȯid]
(pathology)
An abnormal protein deposited in tissues, formed from the infiltration of an unknown substance, probably a carbohydrate.
References in periodicals archive ?
At 36 months, a reduction of amyloid plaque (versus placebo) was observed in all fixed-dose and titration arms in a dose- and time-dependent manner.
1, 2016, highlighted an academic article on "the antibody aducanumab" which reduces beta amyloid plaques in the brain.
For this study, the team used the tracer molecules PIB, Deprenyl and FDG to study the amount of amyloid plaques, inflammatory changes in the form of astrocyte activation, astrocytes being the most common type of glial (supporting) cell in the brain.
"Our initial findings indicate that the spread of tau to widespread cortical regions, in the presence of amyloid plaques, may be the smoking gun--the sign that indicates cognitive impairment is either imminent or underway."
Relative amounts of "good" and "bad" cholesterol in the blood influence the build-up of harmful protein deposits in the brain called beta amyloid plaques, a study found.
5) Prevention of metal toxicity Out of the above fivemainstays, thefeasibility of removing of amyloid plaque and the delaying effect on NFT formation may result in slowing of cognitive decline in the elderly.
The increased production of beta amyloid which may form amyloid plaques is a main characteristic of AD.
Scientists have linked poor sleep with a build up of amyloid plaques - sticky clumps of protein that build up in the brain which are a hallmark of Alzheimer's disease.
The major pathologic findings in the AD brain at autopsy are amyloid plaques (extracellular), neurofibrillary tangles (intracellular), and the loss of synaptic connections.
The next step is to test curcumin on human amyloid plaque formation using newer brain scans and there are plans for that."
"Our molecular imaging approach to AD includes multiple molecular compositions that target AD associated phenomena -- low acetylcholine and amyloid plaque formation.
Results from a study published in the July 16 issue of Proceedings of the National Academy of Sciences revealed that bisdemethoxycurcumin, an ingredient in curcumin, may help clear beta amyloid plaque from the brain.