anabasine

[ə′na·bə‚sēn]

(organic chemistry)

A colorless, liquid alkaloid extracted from the plants Anabasis aphylla and Nicotiana glauca ; boiling point is 105°C; soluble in alcohol and ether; used as an insecticide.

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In an effort to distinguish between nicotine metabolites acquired from smoking vs NRTs in screening of transplant patients, we extended our nicotine panel to include the tobacco alkaloid anabasine, as well as the primary urinary nicotine metabolite trans-3'-hydroxycotinine.

After the analytical validation of our LC-MS/MS-based assay (4), we determined the clinical utility of anabasine to differentiate active smokers from those who were abstaining from smoking or on NRTs.

Anabasine Is a Poor Marker for Determining Smoking Status of Transplant Patients

Figure 1 shows the extracted ion chromatograms for nicotine, cotinine, 3-hydroxycotinine, nornicotine and anabasine at concentrations of 10 ng/mL in extracted human urine.

LCMS/MS advances pharmacologic understanding of Nicotine: accurate and fast determination of nicotine and its metabolites provides a useful method for understanding the pharmacologic effects of nicotine and nicotine addiction

Most samples also contained impurities known to be toxic to humans, such as anabasine, myosmine, and betanicotyrine.

Carcinogens found in e-cigarettes

Keeler and Panter also conducted a round of research to see whether the alkaloid anabasine in wild tree tobacco (Nicotiana glauca)--a plant that is also toxic to livestock--had similar effects on Spanish goats.

Animal scientist finds new vistas in cleft palate research

Compounds of plant origin such as rotenone, nicotine, anabasine, methyl anabasine and lupinine were found effective in killing Culex territans (Diptera: Culicidae) (1).

Laboratory studies on mosquito larvicidal efficacy of aqueous & hexane extracts of dried fruit of Solanum nigrum Linn

In southern Kazakhstan, where anabasine was collected from the wild thickets, 14,000 tons were gathered in a single year and processed at a chemical plant in the city of Chimkent.

3 Humans in the cold deserts and subdeserts

Wood (6) lists some important photochemical products such as pyrethrum, derris, quassia, nicotine, hellebore, anabasine, azadirachtin, d-limonene, camphor and terpenes that have been used as insecticides.

Larvicidal effects of crude extracts of dried ripened fruits of Piper nigrum against Culex quinquefasciatus larval instars

Anabasine, a minor tobacco alkaloid and a biomarker used to check compliance of nicotine replacement therapy, was also included in the assay.

Simultaneous and sensitive measurement of anabasine, nicotine, and nicotine metabolites in human urine by liquid chromatography-tandem mass spectrometry

Anabasine is a tobacco alkaloid present in tobacco products.

Simultaneous analysis of nicotine, nicotine metabolites, and tobacco alkaloids in serum or urine by tandem mass spectrometry, with clinically relevant metabolic profiles

Gas chromatographic-mass spectrometric method for determination of anabasine, antabine and other tobacco alkaloids in urine of smokers and smokeless tobacco users.

Analysis of nicotine, 3-hydroxycotinine, cotinine, and caffeine in urine of passive smokers by HPLC-tandem mass spectrometry

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