The median tumor level above the anal verge
for the patients having AL was 7 cm (ranging from 5 to 10 cm).
The preoperative factors age, histologic grade, lymphovascular invasion, distance from the anal verge
, and type of surgery performed were not associated with a poor failure free survival.
After draping the part, the sulcus between the internal and external sphincters were palpated and each 5 units were injected into intersphincteric space in all the four quadrants, anterior, posterior, left and right side of the anal verge
Common work-up variables include age at diagnosis, gender, tumour biology, distance from anal verge
and immunocytochemical predictors, but to date there are no definitive set of factors identified for prediction of good response.
Colonoscopy revealed a rectal tumor of the ulcerating type located 10cm from anal verge
and biopsy specimens confirmed it to be an adenocarcinoma.
The patient had an ulceroproliferative growth in the sigmoid colon 18 cm from the anal verge
with multiple bilobar liver metastases.
As with cervical HPV infection, infection of the anal verge
with high-risk HPV can result in the development of a high-grade anal cancer precursor lesion (anal intraepithelial neoplasia lAIN] 2/3), which, if not diagnosed and treated, may progress to anal cancer.
In about 20% of cases, the disease extends onto the buttocks and perineum and even into the anal canal, so lesions on the anal verge
should prompt physicians to look in the canal as well.
Most anal squamous cell carcinomas form 34 cm inward from the anal verge
The anal canal begins where the rectal ampulla suddenly narrows (Anorectal junction), passing down and backwards to the anus and ends at anal verge