The anaphase-promoting complex
(APC/C) is a large multi-subunit complex (over 1.2 MDa in humans) composed of approximately 20 different subunits.
Kirschner, "Control of mitotic transitions by the anaphase-promoting complex
," Philosophical Transactions of the Royal Society of London: Series B, Biological Sciences, vol.
 Nonstandard abbreviations: PIP3, phosphatidylinositol 3,4,5-trisphosphate; PKB, protein kinase B; PI3K, phosphatidylinositol 3-kinase; APC, anaphase-promoting complex
A team from The Institute of Cancer Research, London, and the Medical Research Council Laboratory of Molecular Biology in Cambridge produced the first detailed images of the anaphase-promoting complex
Peters, "The anaphase-promoting complex
: proteolysis in mitosis and beyond," Molecular Cell, vol.
Brand, "Independent regulation of synaptic size and activity by the anaphase-promoting complex
," Cell, vol.