(redirected from androgen deprivation)
Also found in: Dictionary, Thesaurus, Medical, Legal.
Related to androgen deprivation: Androgen Deprivation Therapy


the lack of economic and emotional supports generally accepted as basic essentials of human experience. These include income and housing, and parental care (or an adequate substitute) for children. This recognizes that care, shelter and security are human needs (see also HUMANISTIC PSYCHOLOGY, MASLOW) the possession of which leads to a fuller, more comfortable life experience and allows a more complete development of the individual's potential. See also CYCLE OF DEPRIVATION, POVERTY, RELATIVE DEPRIVATION.



sensory insufficiency or inadequate load on the system of analysors observed in man when isolated or when the functioning of the main sense organs is impaired. Astronauts, speleologists, and others experience the phenomenon of deprivation. The depth of the psychological, autonomic, and somatic changes in deprivation is determined chiefly by its intensity and duration, as well as by individual personality traits. If work capacity and mental health are to be retained under conditions of deprivation, it is very important that the work be organized efficiently and that specific steps be taken to increase the reliability of the auditory, visual, interoceptive, and other information.


Banshchikov, V. M., and G. V. Stoliarov. “Sensornaia izoliatsiia.” Zhurnal nevropatologii ipsikhiatrii im. S. S. Korsakova, 1966, no. 9, pp. 1428–40.
References in periodicals archive ?
Key clinical point: Forgoing androgen deprivation therapy cuts rather than raises overall and cardiac mortality in certain patients with prostate cancer, according to their comorbidities.
Researchers ultimately determined that intermittent androgen deprivation does not achieve comparable survival rates compared to complete androgen deprivation therapy, though it does provide small improvements in quality of life (i.
The team's hypothesis is that metastatic prostate cancer patients with the weakest response to androgen-deprivation therapy could be given GCP concurrently with androgen deprivation therapy to retain Filamin A in the nucleus, thereby allowing cancer cells to die off.
The Impact of Exercise on Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer
28,29) Androgen deprivation can be achieved surgically or by medical castration, which can be performed by the administration of estrogens and gonadotropin-releasing agonists and antagonists, and has been shown to be effective in treating advanced and metastatic disease in several large clinical trials.
9] If AR were upregulated after a prolonged period of androgen deprivation thus making cancer cells more sensitive to anti-androgens, then we might have expected a longer period of PSA response.
NASDAQ: GTXI) today announced that the results of the Phase III clinical trial evaluating toremifene citrate 80 mg for the treatment of multiple side effects of androgen deprivation therapy (ADT) for advanced prostate cancer will be presented during a late breaking oral presentation at the 2008 Annual Meeting of the American Association for Cancer Research being held in San Diego April 12 - 16.
7] Medical ADT is often favoured over orchiectomy because of the potential for intermittent androgen deprivation, lack of procedural complications and possible psychological benefits.
Although androgen deprivation therapy is currently a treatment option for these men, the associated sequelae, including loss of libido, fatigue, anemia, cognitive impairment and osteoporosis, make this therapy unattractive to many patients.
NASDAQ: GTXI) today announced that toremifene citrate 80 mg reduced hot flashes in men with prostate cancer on androgen deprivation therapy (ADT), a key secondary endpoint of the Phase III clinical trial evaluating toremifene citrate 80 mg for the treatment of multiple side effects of ADT for advanced prostate cancer.
In the landmark EORTC (European Organisation for Research and Treatment of Cancer) 22863 trial, overall survival (OS) and local control were considerably improved with the use of 3 years of adjuvant androgen deprivation therapy (ADT) when given with external beam radiotherapy (EBRT) in patients with high-risk locally advanced disease (90% had cT3/T4).

Full browser ?