androstenedione


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Related to androstenedione: DHEA, androstenediol

androstenedione

[¦an·drō·stə¦ned·ē‚ōn]
(biochemistry)
C19H26O2 Any one of three isomeric androgens produced by the adrenal cortex.
References in periodicals archive ?
According to the study, "Salivary testosterone, cortisol, DHEA and androstenedione levels did not change overall or between play against people vs.
Adrenal-derived DHEA-S and DHEA is converted by 3[beta]-hydroxysteroid dehydrogenase (3[beta]-HSD) into androstenedione and testosterone --the latter being the downstream metabolite of androstenediol produced from DHEA via I7[beta]-HSD Type V, which is in close proximity to 3[beta]-HSD In the prostate epithelium.
17-OHP, androstenedione, and testosterone were detected without derivatization following reconstitution in methanol:water (50:50 vol/vol).
17-[beta]-HSD3 deficiency (OMIM: 264300) is a rare autosomal recessive disorder of male sex differentiation (pseudohermaphroditism) resulting from a defect in the last reversible step of steroidogenesis in testosterone biosynthesis in the testes in which androstenedione is converted into testosterone.
Some of the majorly marketed sports supplements are androstenedione (natural steroids that can be broken down into testosterone), creatine (most effective for athletes doing intermittent high-intensity exercise with short recovery intervals such as sprinting and power lifting) and fat burners (acting as a stimulant which increases metabolism and helps in reducing weight).
This was a surprising finding indicating certain androgens, particularly testosterone and androstenedione, appear to have more of an effect on blood vessel development compared to dihydrotestosterone.
Materials: Androstenedione, Diethylstilbestrol (DES), equine chorionic gonadotrophic (eCG) and human chorionic gonadotrophic (hCG) hormones, follicle stimulating hormone (FSH), Hanks Balanced Salt Solution (HBSS), Dulbecco's Minimal Essential Medium (DMEM-F12), penicillin/ streptomycin, trypsin-EDTA, poly-L-lysine and 18a glycyrrhetinic acid (18[alpha]GA) were purchased from Sigma Chemical Co.
Second, Androstenedione (Andro) which is an androgenic steroid produced by the testes, adrenal cortex, and ovaries.
Present in both males and females, the principle androgens are testosterone and androstenedione.
Adrenocortical carcinoma usually presents with dysfunctional uterine bleeding in women with increased amounts of androstenedione and estrogens that results in Cushing's syndrome, suggesting inefficient conversion of cortisol (4).
The resultant loss of hormone production in premenopausal women is obvious but 'postmenopausal ovaries continue to produce significant amounts of testosterone and androstenedione, which are converted to estrogen peripherally'.