Certain severe BDs were associated with a high risk for in-hospital death, particularly anencephaly
(85.3%) (Table 1).
The only exceptions could have been cases with unequivocal diagnosis of anencephaly
at one of the two regional hospitals (although these are usually referred to TAH).
The findings also provide important clues into the diet of the baby's mother and hint at a lack of foods containing folic acid, which plays a critical role in the development of the neural tube and can lead to anencephaly
, if not provided sufficiently.
JJ's birth month of May is anencephaly
awareness month and the courageous parents are already determined their "little fighter" will make a difference.
These findings were consistent with those of craniospinal rachischisis totalis (anencephaly
with rachischisis totalis).
For case 1, although Zika virus was demonstrated in multiple tissues of the fetus, the birth defect identified (anencephaly
) is not on the recognized spectrum of congenital infection.
Almost all babies with anencephaly
die before birth or within a few hours or days after birth.
A 28-year-old female (gravida 2, para 2) was transferred from an outside facility for ultrasonographic features concerning anencephaly
. The fetus was initially diagnosed as anencephaly
at approximately 14 weeks of estimated gestational age (EGA).
High posterior odds ratios were observed for five birth defects with paroxetine use: anencephaly
(3.2); atrial septal defects (1.8); right ventricular outflow tract obstruction defects (2.4); gastroschisis (2.5); and omphalocele (3.5).
In August 2014, a total of 19 population-based birth defects surveillance programs in the United States reported to CDC the number of cases of spina bifida (International Classification of Diseases, 9th Revision, Clinical Modification codes 741.0 and 741.9) and anencephaly
(codes 740.0-740.1) among deliveries occurring during 1995-2011 among non-Hispanic whites, non-Hispanic blacks, and Hispanics, as well as all racial/ethnic groups combined.
Neural tube defects (NTDs) including anencephaly
SB and encephalocele are among the most severe and frequent birth defects though they are amenable to preventions with folic acid fortification or supplementation.4 Of all congenital anomalies NTDs are the easiest to identify prenatally.
The most serious form, anencephaly
, means that the baby will not live beyond birth, and many babies born with spina bifida face a life with serious multiple disabilities.