aneuploidy


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Related to aneuploidy: aneuploidy screening, Turner syndrome

aneuploidy

[′a·nyü‚plȯid·ē]
(genetics)
Deviation from a normal haploid, diploid, or polyploid chromosome complement by the presence in excess of, or in defect of, one or more individual chromosomes.
References in periodicals archive ?
Aneuploidy screening has been reported to increase the chance of successful embryo implantation, decreases miscarriage rate, and reduce the chance of having a child with a chromosome abnormality).
Indications for prenatal diagnostic testing were: maternal age, abnormal results of aneuploidy screening (combined first-trimester or biochemical second-trimester screening for DS >1/300 or 1:150 for trisomy 13 or 18), abnormal structural findings in fetal ultrasound (including increased nuchal translucency [greater than or equal to]3.
Orthogonal fetal aneuploidy classification results were unavailable from these patients; however, since the performance of MaterniT21 PLUS has been extensively described previously (8, 9, 12, 13), the truth for each sample was defined as the result from the MaterniT21 PLUS LDT.
12] The American College of Obstetricians and Gynecologists committee opinion on cfDNA screening for fetal aneuploidy also cautions about the use of cfDNA screening in low-risk populations, as there are limited data on cost-effectiveness in this group.
Aneuploidy is an unusual number of chromosome, typically characterized by the absence of one copy of a single chromosome or by the increase in the amount of chromosomes.
Five of the 11 SMFM 2015 publications involved cell-free DNA screening for fetal aneuploidy, reflecting the many changes and updates to this ever-evolving topic.
Her first child has no known chromosomal abnormalities and she has no family history of aneuploidy.
We also aimed to determine the sex ratio in the first trimester and compare the rate of aneuploidy in sporadic abortion with that of recurrent abortion.
Perhaps, cancer prevention can go even one step further and identify factors that decrease aneuploidy and encourage cells to remain diploid.
A polymerase chain reaction (PCR) aneuploidy screen performed on a peripheral blood sample diagnosed Trisomy 13.
In embryos at high risk of aneuploidy, these two steps occur about six hours later on average, so time-lapse imaging can be used to pick low-risk embryos for implantation.
Aneuploidy originates from chromosome segregation errors during the two highly regulated programs of cell division: mitosis and meiosis.