aneuploidy


Also found in: Dictionary, Thesaurus, Medical, Wikipedia.
Related to aneuploidy: aneuploidy screening, Turner syndrome

aneuploidy

[′a·nyü‚plȯid·ē]
(genetics)
Deviation from a normal haploid, diploid, or polyploid chromosome complement by the presence in excess of, or in defect of, one or more individual chromosomes.
References in periodicals archive ?
Fluorescence in situ hybridization detects increased sperm aneuploidy in men with recurrent pregnancy loss.
Aneuploidy (an abnormal number of chromosomes) is the most frequent genetic disorder observed in live births and miscarriages, with trisomies being the most prevalent, accounting for approximately 53 percent of all chromosome abnormalities.
Rapid diagnosis of aneuploidy in chromosomes 13, 18, 21, X and Y by quantitative fluorescence-PCR combined with short tandem repeat and fluorescence-labeled homologous gene quantitativePCR using 4-color fluorescently labeled universal primers.
Is it time to sound an alarm about false-positive cell-free DNA testing for fetal aneuploidy? Am J Obstet Gynecol 2013;209:415-9.
The introduction of preimplantation genetic diagnosis into clinical practice revealed that Robertsonian translocation often leads to aneuploidy. In this case, parts of acrocentric chromosomes are exchanged in a way in which the satellite region is lost and two chromosomes remain coupled, so that this embryo contains 45 chromosomes.
Growth in this segment can be attributed to the increasing maternal age, rising incidence of aneuploidy disorders, and strategic initiatives by key players to provide technologically advanced PGS products for aneuploidy screening.
With the recent impetus on first-trimester screening for aneuploidy and availability of high-resolution transducers, agenesis of DV can be diagnosed in the first trimester.
Of the total number of second-trimester ultrasound scans done (n=66), 14 (21.2%) detected a variety of markers of aneuploidy. Eight of these patients only had a second-trimester ultrasound scan, and 6 had prior CFTS.
DNA sequencing versus standard prenatal aneuploidy screening.
[sup][1],[2] Chromosome aneuploidy and polyploidy consist of more than 96% of chromosomal abnormalities in spontaneous abortion and X, Y, 13, 16, 18, 21, and 22 are frequently involved.
All carcinogens cause aneuploidy, even though they may not cause genes to mutate.