This group of tumors in the spleen is composed of heterogeneous tumors such as hemangioma, angioendothelioma (AE), littoral cell angioma, and angiosarcoma.
Myoid Angioendothelioma of the Spleen: A Rare Case Report and Literature Review.
Keywords * Spleen * Malignancy * Myoid angioendothelioma
The HHV8 specificity and sensibility is increased by its positivity in Kaposi-like lesions present in sarcoma, and decreased by its negativity in angiosarcoma, kaposiform hemangioendothelioma, hemangioma with fusiform cells, reactive angioendothelioma
or reactive vascular proliferations [14, 21].
The differential diagnosis of intravascular KS includes intravascular papillary endothelial hyperplasia, intravenous PG, intravascular fasciitis, papillary intralymphatic angioendothelioma
(Dabska tumor), and intravascular myopericytoma.
Clinically, IPEH can be misdiagnosed as a mucocele, hemangioma, pyogenic granuloma, Kaposi sarcoma, angiosarcoma, Kimura disease, intravenous atypical vascular proliferation, endovascular papillary angioendothelioma, papular angioplasia, or bacillary angiomatosis.
Endovascular papillary angioendothelioma of childhood: A vascular lesion possibly characterized by "high" endothelial cell differentiation.
Malignant endovascular papillary angioendothelioma
of the skin in childhood: clinicopathologic study of 6 cases.
49,50] Other differential diagnoses include mucocele,  pyogenic granuloma,  Kaposi' s sarcoma,  and other vascular conditions such as hemangioma, angioendothelioma
, papular angioplasia, Kimura's disease, bacillary angiomatosis, and intravenous atypical vascular proliferation.
Cell proliferation in malignant angioendothelioma
during sequential chemotherapy.