Recently, intravitreally administrated bevacizumab, a vascular endothelial growth factor (VEGF) inhibitor that is a full size antibody to all isoforms of VEGF-A, has been successfully used as an off label treatment on CNV secondary to angioid streaks
of the fundus are the most common ocular findings and are associated with pseudoxanthoma elasticum 85% of the time.
Fundoscopic examination revealed angioid streaks
around the optic discs and peau d'orange appearance in the temporal macula of both eyes.
8 Characteristic ocular defect is angioid streaks
of retina, reddish-brown curvilinear bands that radiate from the optic disk.
Five of the most common causes are exudative macular degeneration, high/ pathological myopia, choroidal rupture, angioid streaks
, and punctate inner choroidopathy.
Ayrica LCAT eksikliginde fundusta angioid streaks
benzeri bruch membran rupturu saptanan olgular bildirilmistir.
is a hereditary condition resulting in a degeneration of Bruch's membrane and the RPE.
Rare associations include retinitis pigmentosa (RP) and angioid streaks