Keywords: cerebral amyloid angiopathy
, hemorrhagic stroke, intracerebral hemorrhage, stroke
These results support the notion that EPVS in the BG may be a marker of CSVD., The results of a prospective cohort study showed that WM-EPVS was associated with cerebral amyloid angiopathy
(CAA) and superficial siderosis. Conversely, a prospective, multicenter, hospital-based study published by Zhang et al . showed that hypertension was an independent risk factor for EPVS in WM but not in BG or hippocampus.
The potential explanation lies in the following: cerebral amyloid angiopathy
represents the pathohistological basis of the lobar pICH, while vasculopathy of deep perforated arteries is a characteristic of the deep cerebral localization [23, 24].
Lobar hemorrhages are usually associated with cerebral amyloid angiopathy
, arteriovenous malformations, brain tumors, or other structural lesions.
Determining the risk factors for the development of micro- and macrovascular angiopathy
is important in order to attempt to reduce the burden from disease complications.
Thus, cardiovascular disease may promote and contribute to the development of AD, and in a parallel way, AD could also contribute to vascular damage and cerebral hypoperfusion progression through cerebral amyloid angiopathy
and other mechanisms .
Nevertheless, the intraocular production of TTR V30M by the retinal and ciliary pigment epithelium remains unchanged, contributing to the progression of amyloid deposition-associated ocular manifestations such as abnormal conjunctival vessels, dry eye, scalloped pupils, deposition of amyloid on the anterior surface of the lens and on the pupil border, vitreous amyloidosis, glaucoma, and retinal angiopathy
. Moreover, their prevalence increases over time .
ICH can also arise as a secondary effect of other pathologies including cerebral amyloid angiopathy
and Alzheimer's disease.
Cortical and leptomeningeal arterioles had mild cerebral amyloid angiopathy
. Tau immunostaining demonstrated neurofibrillary pathology, largely restricted to limbic regions with mild hippocampal NFT pathology.
In 1984, Glenner and Wong purified a 4.2 kDa [beta]-amyloid (A[beta]) from a patent with Alzheimer's disease (AD) with cerebral amyloid angiopathy
With haemorrhagic stroke, the main causes include: vascular intracranial malformations; aneurysms, haemangiomas, atrial venous malformations; cerebral amyloid angiopathy
; hypertension, coagulation disorders; and illicit drugs.
Banode, "Reversible cerebral angiopathy
after blood transfusion," Asian Journal of Transfusion Science, vol.