Schalekamp, "Metabolism of angiotensin I
by different tissues in the intact animal," The American Journal of Physiology--Heart and Circulatory Physiology, vol.
Ferrario, "In vivo metabolism of angiotensin I
by neutral endopeptidase (EC 18.104.22.168) in spontaneously hypertensive rats," Hypertension, vol.19,supplement6, pp.692-696,1992.
A quantitative in silico analysis calculates the angiotensin I
converting enzyme (ACE) inhibitory activity in pea and whey protein digests.
This approach, it may be argued, is purely analytical, and a slight degradation of angiotensin I
over time could have had an important impact on the low values measured in this study.
The pilot study did suggest one potential patient population for whom the ACE inhibitor/ angiotensin I
receptor blocker combination may be helpful: patients with nonobstructive hypertrophic cardiomyopathy and diastolic dysfunction with preserved LV systolic function.
To evaluate the effect of the standardized aqueous extract (AE) of Cecropia glaziovii Sneth on the plasma angiotensin I
converting enzyme (ACE-EC 22.214.171.124) activity, rats were treated with a single dose of AE (1 g/kg, p.o.) or repeatedly (0.5 g/kg/bid, p.o.) for 60 days.
MADRID -- Angiotensin I
receptor blockade with losartan improves insulin sensitivity independent of its effects on blood pressure in hypertensive individuals at risk for metabolic syndrome, reported Dr.
Normally, ACE converts the compound angiotensin I
into angiotensin II, which induces the blood vessels to constrict and blood pressure to rise.
The angiotensin I
converting enzyme gene and predisposition to high blood pressure.
ACE is an enzyme that converts one of the body's chemical messengers, angiotensin I
, into angiotensin II.
Angiotensin-converting enzyme (ACE; EC 126.96.36.199) catalyzes the formation of angiotensin II by cleaving the C-terminal histidylleucine dipeptide from angiotensin I