angiotensin

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angiotensin

[‚an·jē·ə′ten·sən]
(biochemistry)
A decapeptide hormone that influences blood vessel constriction and aldosterone secretion by the adrenal cortex. Also known as hypertensin.
References in periodicals archive ?
2005) Blood pressure response to strength training may be influenced by angiotensinogen A-20C and angiotensin II type I receptor A1166C genotypes in older men and women.
20) reported that weight reduction is associated with a reduction of angiotensinogen levels, renin, aldosterone and ACE activity, as well as the reduction of angiotensinogen levels, which was highly correlated with a decline in waist circumference.
When oxidative stress is present, the angiotensinogen molecule shifts its shape and floods the system with angiotensin
Detection of putative functional angiotensinogen (AGT) gene variants controlling plasma AGT levels by combined segregation-linkage analysis.
Blood pressure is linked to salt intake and modulated by the angiotensinogen gene in normotensive and hypertensive elderly subjects.
The findings, published in the journal Nature, showed that angiotensinogen is oxidised and changes shape to permit access by the enzyme renin.
In the obese state, the expression of adipocytokines such as resistin, interleukin-6 (IL-6), tumor necrosis factor-[alpha] (TNF-[alpha]), plasminogen activator inhibitor-1 (PAI-1), monocyte chemotactic protein-1 (MCP-1), and angiotensinogen is increased in enlarged adipocytes, causing insulin resistance and metabolic disorders.
Renin which is secreted from juxtaglomerular cells in the kidney acts on angiotensinogen and converts it into angiotensin I [6].
The decreased perfusion stimulates the production of renin from the J-G cells which then enters the blood and reacts with h angiotensinogen to form angiotensin I.
3), (4) Pathophysiology of DN is hyperglycemia-induced angiotensinogen gene expression, inducible nitric oxide synthetase (iNOS) expression, and oxidative stress in renal cells.

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