While most .22 pistols feature the raked-back angle better suited to feeding the rimmed .22 LR cartridges, shooters required to shoot an M1911 in competition preferred a rimfire with a grip angle closer
to that of the .45.
Instead, the team found that the fastest debris, ejected at the initial stages of crater formation, tended to depart at an angle closer
to 30 degrees more of a sideways spray than an upward trajectory.
In theory if a typist were to type on a negatively sloped keyboard with a wrist extension angle closer
to a neutral posture than the approximately 200 extension with a conventional keyboard, then the typist would be less susceptible to WMSDs.