animal(redirected from animal models of human disease)
Also found in: Dictionary, Thesaurus, Medical, Legal.
animal, any member of the animal kingdom (kingdom Animalia), as distinguished from organisms of the plant kingdom (kingdom Plantae) and the kingdoms Fungi, Protista, and Monera in the five-kingdom system of classification. (Another classification system, suggested by genetic sequencing studies, places animals with plants and some other forms in a larger taxonomic unit called the eukarya to distinguish them from the prokaryotic bacteria and archaea, or ancient bacteria.)
Essentially, animals are many-celled heterotrophic organisms. Plants and algae characteristically manufacture their food from inorganic substances (usually by photosynthesis); animals must secure food already organized into organic substances. They are dependent upon photosynthetic organisms, which provide oxygen as a byproduct and are the ultimate source of all their food. Animals (as well as plants) provide carbon dioxide through respiration and the decomposition of their dead bodies (see carbon cycle; nitrogen cycle). In addition, most animals have specialized means of locomotion, generally involving muscle cells, and possess nervous systems and sense organs—all adaptations for securing food. In most forms there is a distinct alimentary canal or digestive system. Animal cells do not have cell walls. Almost all animals, unlike most plants, possess a limited scheme of growth; that is, the adults of a given species are nearly identical in their characteristic form and are similar in maximum size. Most animals reproduce sexually, but some are capable of asexual reproduction under certain circumstances.
With the advent of electron microscopy and advanced biochemical analyses, intricate differences between simple and microscopic organisms were better understood, and many that were previously fit into the animal or plant kingdom were then placed into separate kingdoms (i.e., Monera for the bacteria, Protista for the algae and protozoans, and so forth). In zoological classification the animal kingdom has been divided into the three subkingdoms of Parazoa (the sponges), Mezozoa (wormlike parasites), and Eumetazoa. Eumetazoa comprises numerous invertebrate phyla and the phylum Chordata. The chordates include two primitive subphyla of a few species each and the subphylum Vertebrata (see vertebrate). There are at least 1.5 million animal species; approximately 95% of these are invertebrates.
The scientific study of animals is called zoology; the study of their relation to their environment and of their distribution is animal ecology. For specific approaches to the study of living things, see biology.
Any living organism which possesses certain characteristics that distinguish it from plants. There is no single criterion that can be used to distinguish all animals from all plants. Animals usually lack chlorophyll and the ability to manufacture foods from raw materials available in the soil, water, and atmosphere. Animal cells are usually delimited by a flexible plasma or cell membrane rather than a cell wall. Animals generally are limited in their growth and most have the ability to move in their environment at some stage in their life history, whereas plants are usually not restricted in their growth and the majority are stationary.
The presence or lack of chlorophyll in an organism does not determine its affinity to the plant or animal kingdom. Among the protozoa, the class Phytamastigophora includes animals, such as the euglenids, which have chromatophores containing chlorophyll. These organisms are considered to be animals by zoologists and plants by phycologists. Higher parasitic plants and the large plant group Fungi also lack chlorophyll. Another borderline group is the slime molds: the Mycetozoa of zoologists and the Myxomycophyta of the botanists; these organisms exhibit both plant and animal characteristics during their life history. Movement is not a characteristic restricted to the animal kingdom; many of the thallophytes such as Oscillatoria, numerous bacteria, and colonial chlorophytes are motile.
Classifying organisms as plants or animals is difficult. Today biologists recognize up to five kingdoms. Most place the one-celled animals and plants, sometimes along with algae and certain other groups, into the Protista. Other kingdoms are the Monera for the bacteria and blue-green algae, and the Fungi for the slime molds and true fungi. These schemes for recognizing additional kingdoms have the practical advantage of eliminating the difficulties of delimiting and describing the kingdoms of multicellular animals and plants. See Animal kingdom, Plant, Plant kingdom