and anisokaryosis were moderate; occasional fine pink extravascular material was associated with cell aggregates.
It thus postulated that it is conceivable that the free cholesterol in excess within the primary atherosclerotic lesion may originate from other cellular sources, including RBCs, and that anisocytosis
may directly participate in the pathogenesis of cardiovascular disease (CVD) through a variety of mechanisms.
The reduction in hemoglobin, packed cell volume, RBCs and blood pictures of hypochromasia, poikilocytosis and anisocytosis
were indicating anaemia which is mainly due to hemolysis by Babesia canis and also due to decreased RBC production, excessive consumption and/or destruction of blood cellular component, decreased RBC survival and lack of erythropoitic response in Ehrlichiosis as suggested by Warner (2008).
They thought that inflammation and thromboembolism resulted with anisocytosis
, causing elevation of RDW (5).
At approximately 16 months of age, a complete blood count (CBC) showed a platelet count of 104,000/uL, increased red cell distribution width (RDW, 17.1%), anisocytosis
, and microcytosis.
They suggested a possible mechanism of the adverse effects of chronic inflammation on erythropoiesis and thus anisocytosis
occurrence via direct erythroid precursor's suppression reduces the production of erythropoietin by kidneys, reduces the iron bioavailability, and induces apoptosis and increases the resistance to erythropoietin of the erythroid precursor cell line.
Urch et al., "Clinical and prognostic significance of anisocytosis
measured as a red cell distribution width in patients with colorectal cancer," QJM, vol.
Caption: Figure 4: Binocular hepatocytes with anisocytosis
Blood film showed anisocytosis
and small number of pencil cells.
Hypochromic microcytic red cell in proportion to degree of anaemia, with poikilocytosis anisocytosis
, pencil cells, red cell count less than 5 million/mm3 and MCV less than 75fl usually favors iron deficiency.
The most important diagnostic feature of cancer cells are anisonucleosis, anisocytosis
, abnormal nuclear texture and nuclear hyperchromasia and abnormal N/C ratio.
Red cell distribution width (RDW) is a quantitative measurement of difference in the size of circulating erythrocytes, which has a high value if greater heterogeneity in cell dimensions is present (i.e., anisocytosis