ankyrin


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ankyrin

[aŋ′kī·rən]
(cell and molecular biology)
A protein found in the cell membrane of erythrocytes that attaches the membrane to the cytoskeleton protein spectrin.
References in periodicals archive ?
The study also found that nicotine produced these negative effects by stimulating the ion channel transient receptor potential ankyrin 1 (TRPA1).
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder.
Two SNPs were located on a narrow region of chromosome 4 (from 15.59 Mb to 16.04 Mb), and the nearest genes were inhibitor of apoptosis protein 3 (IAP3) and sosondowah ankyrin repeat domain family member D (SOWAHD).
However, it was proven that the SNP rs1800497 is a part of the exon 8 of ankyrin repeat and protein kinase domain-containing protein 1 (ANKK1) gene [4].
In this animal model, parenterally administered dipyrone and antipyrine, but not MAA, blocked the transient receptor potential ankyrin 1 (TRPA1) channel.
Ankyrin repeat domain 26 (ANKD26)-related thrombocytopenia is a rare inherited form of autosomal dominant thrombocytopenia.
DARPins (Designed Ankyrin Repeat Proteins) are artificial proteins that recognize and bind antigens.
Transient receptor potential ankyrin 1 (TRPA1) was initially characterized as a thermoreceptor activated by temperatures [less than or equal to]17[degrees]C (10).
(3,4) The lipid bilayer and the membrane cytoskeleton are linked by the interaction of Band 3 and RhAG with ankyrin. Glycophorin, XK, Rh, and Duffy interact with protein 4.1R.
(5) Neurovascular signaling is also aberrantly upregulated; vanilloid and ankyrin receptors have been shown to be active in rosacea, and are activated by rosacea-exacerbating stimuli, such as heat, inflammation, and spices.
The primary lesion is reduced deformability of erythrocytes due to defects in the membrane protein ankyrin, spectrin, or protein 4.2 (1).