antagonist


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antagonist

1. any muscle that opposes the action of another
2. a drug that counteracts the effects of another drug
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005

antagonist

[an′tag·ə‚nist]
(biochemistry)
A molecule that bears sufficient structural similarity to a second molecule to compete with that molecule for binding sites on a third molecule.
(pharmacology)
A drug or other chemical substance capable of reducing the physiological activity of another chemical substance; refers especially to a drug that opposes the action of a drug or other chemical substance on the nervous system by combining with and blocking the nerve receptor.
(physiology)
A muscle that contracts with, and limits the action of, another muscle, called an agonist, with which it is paired.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in classic literature ?
In this second encounter, the Templar aimed at the centre of his antagonist's shield, and struck it so fair and forcibly, that his spear went to shivers, and the Disinherited Knight reeled in his saddle.
``We shall meet again, I trust,'' said the Templar, casting a resentful glance at his antagonist;
De Grantmesnil's horse, which was young and violent, reared and plunged in the course of the career so as to disturb the rider's aim, and the stranger, declining to take the advantage which this accident afforded him, raised his lance, and passing his antagonist without touching him, wheeled his horse and rode back again to his own end of the lists, offering his antagonist, by a herald, the chance of a second encounter.
A second and a third party of knights took the field; and although they had various success, yet, upon the whole, the advantage decidedly remained with the challengers, not one of whom lost his seat or swerved from his charge misfortunes which befell one or two of their antagonists in each encounter.
In action they flew to get behind or over the Germans: they even dashed underneath, avoiding only passing immediately beneath the magazine, and then as soon as they had crossed let fly with their rear gun, and sent flares or oxygen shells into the antagonist's gas-chambers.
Another German burnt, and one badly deflated by the prow of an antagonist, flopped out of action southward.
One of them flared down and vanished far away in the north; two dropped with something twisted and crippled in their movements; then a group of antagonists came down from the zenith in an eddying conflict, two Asiatics against one German, and were presently joined by another, and drove away eastward all together with others dropping out of the German line to join them.
There seemed, however, a steady attempt to isolate antagonists, to cut them off from their fellows and bear them down, causing a perpetual sailing back and interlacing of these shoaling bulks.
Both Number Twelve and Number Three had assured him that the beasts had not recaptured her, for they had seen the entire band flee madly through the jungle after hearing the report of the single shot which had so terrorized Bulan's antagonists. Bulan did not know what to make of this occurrence which he had not himself heard, the shot having come after he had lost consciousness at the foot of the tree; but from the description of the noise given him by Number Twelve he felt sure that it must have been the report of a gun, and hoped that it betokened the presence of Virginia Maxon's friends, and that she was now safe in their keeping.
The analyst notes that Myovant's lead product relugolix is poised to become the second gonadotropin releasing hormone antagonist for treating endometriosis and uterine fibroids, and maintains her positive outlook on the GnRH antagonists market, which she believes could grow to over $4.5B in sales in 2025 and support multiple products.
ENPNewswire-August 7, 2019--Spring Bank Announces Collaborative Research Agreement with University of Texas Southwestern Medical School for Evaluation of STING Antagonist Compounds
The antiemetics market is segmented by type of drugs into different categories such as 5-HT3 receptor antagonists, Dopamine antagonists, NK1 receptor antagonist, Antihistamines (H1 histamine receptor antagonists), Cannabinoids, Benzodiazepines, Anticholinergics, Steroids and Others.