antagonist

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Related to antagonist medication: Partial agonist

antagonist

1. any muscle that opposes the action of another
2. a drug that counteracts the effects of another drug

antagonist

[an′tag·ə‚nist]
(biochemistry)
A molecule that bears sufficient structural similarity to a second molecule to compete with that molecule for binding sites on a third molecule.
(pharmacology)
A drug or other chemical substance capable of reducing the physiological activity of another chemical substance; refers especially to a drug that opposes the action of a drug or other chemical substance on the nervous system by combining with and blocking the nerve receptor.
(physiology)
A muscle that contracts with, and limits the action of, another muscle, called an agonist, with which it is paired.
References in periodicals archive ?
Tumor necrosis factor alpha (TNF-[alpha]) antagonist-induced lupus-like syndrome (TAILs) (1) is characterized by rashes, arthralgias, fever, and/or serositis along with positive lupus serologies temporally associated with initiation of TNF-[alpha] antagonist medications. (2) The incidence of TAILs may be increasing as TNF-[alpha] antagonists are more widely utilized.
POSSIBLE DRUG DRUG NAME INTERACTIONS Namenda[R] (memantine) Other NMDA antagonist medications, Blocks the toxic effects including amantadine, an antiviral used to associated with excess treat the flu, dextromethorphan, prescribed glutamate and regulates to relieve coughs due to colds or flu, and glutamate activation.
Patients were randomized to receive losartan (Cozaar) or placebo, both taken in addition to conventional anti-hypertensive therapy (but not including renin-angiotensin-aldosterone system antagonist medications).